Prior research has shown that the predictive power of a stress-health model can be improved by the addition of sleep as a predictor variable. However, negative affect (NA) may act as a confounding variable in stress-health relationships: a source of bias that potentially inflates the observed relationship between stress and health. The current study examines whether stress and sleep remain significant predictors of health after controlling for trait NA. An online survey containing well-established measures of stress, sleep, health, and NA was completed by 460 undergraduates. Hierarchical regression analyses revealed that stress and sleep remained significant predictors of self-reported health after controlling for the effects of NA. Our findings support the notion that stress-health models can be improved by the integration of sleep as an additional predictor variable and demonstrate that the stress/sleep-health relationships are not fully explained by dispositional NA. From a theoretical perspective, the inclusion of NA measures allows researchers to tease apart the unique contributions of predictor variables. This knowledge can subsequently be put to the test with greater confidence in the design of interventions that seek to improve health through stress reduction and improved sleep.
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Pharmacol Rep
January 2025
Razi Drug Research Centre, Iran University of Medical Sciences (IUMS), Tehran, Iran.
Melatonin, renowned for regulating sleep-wake cycles, also exhibits notable anti-aging properties for the skin. Synthesized in the pineal gland and various tissues including the skin, melatonin's efficacy arises from its capacity to combat oxidative stress and shield the skin from ultraviolet (UV)-induced damage. Moreover, it curbs melanin production, thereby potentially ameliorating hyperpigmentation.
View Article and Find Full Text PDFMil Med
January 2025
San Diego State University School of Public Health, San Diego, CA 92182, USA.
Introduction: High occupational stress is generally associated with poorer mental health and reduced performance in military personnel, whereas access to support resources is associated with positive outcomes. However, little research has examined the unique stressors and supports experienced by sailors on ships while underway at sea. The objectives of this study were to (1) identify sailors' underway stressors and supports and (2) examine how these differ as a function of demographic and operational factors.
View Article and Find Full Text PDFBMJ Nutr Prev Health
December 2024
Region Kalmar County Hospital, Kalmar, Sweden.
Background: Several modifiable risk factors, including dietary habits, are linked to cardiovascular disease (CVD) progression. However, lifestyle changes remain notoriously challenging, perhaps due to psychosocial factors. This pilot study aims to investigate the relationship between adherence to a healthy diet, CVD risk factors, psychological factors and sociodemographic variables among middle-aged adults in Sweden.
View Article and Find Full Text PDFBiochem Biophys Rep
March 2025
Institute for Chronobiology, Foundation for Advancement of International Science (FAIS), 3-24-16 Kasuga, Tsukuba, Ibaraki, 305-0812, Japan.
Gaucher's disease (GD) is a genetic disease characterized by a mutation in the metabolic enzyme glucocerebrosidase (GBA1), leading to the accumulation of glucosylceramide in tissues. We previously discovered that a -inserted mutation in the gene of fruit flies, , mimics human neuronopathic GD (nGD) characteristics, providing a promising model for studying the molecular mechanisms of the disease. We also reported that extremely low-frequency electric fields (ELF-EFs) promote sleep and extend the lifespan of wild-type flies.
View Article and Find Full Text PDFCureus
December 2024
Department of Family Medicine, Ministry of the National Guard-Health Affairs, King Abdulaziz Medical City, King Abdullah International Medical Research Center, Jeddah, SAU.
In the growing field of geriatric psychiatry, the "3 Ds"-depression, dementia, and delirium-are a complex clinical challenge, especially in patients with medical comorbidities. This is a case report of a 96-year-old Saudi woman with chronic kidney disease, heart failure, and recurrent hyponatremia presented with worsening sleep, depression, persecutory delusions, and hallucinations following an intensive care unit (ICU) stay for urinary tract infection. Examination revealed cognitive decline and depressive symptoms, with sodium at 123 mmol/L.
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