An efficient and highly productive rhodium-catalyzed method for the synthesis of nitriles employing aldehydes or ketones, methyl cyanoacetate, water and carbon monoxide as starting materials has been developed. Simple rhodium chloride without any ligands can be used. The fine tuning of the substrate can lead to the activity higher than 5000 TON.
Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1039/c8ob01992d | DOI Listing |
Publication Analysis
Top Keywords
aldehydes ketones
8
formal reductive
4
reductive addition
4
addition acetonitrile
4
acetonitrile aldehydes
4
ketones efficient
4
efficient highly
4
highly productive
4
productive rhodium-catalyzed
4
rhodium-catalyzed method
4
Similar Publications
Want AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!