The HPA axis exploration in the endogenous depressions indicates an hyperactivity of this system. But the reason of this perturbation is not definite. The corticotropin-releasing factor (CRF) test has been described from research work carried out by Vale et al. In the endogenous depressions, this test enables us to specify physiopathological factors of the HPA axis dysfunction. Some research suggest an hypothalamic and limbic CRF hypersecretion in the endogenous depressions. But the results are not consistent principally because of the diversity of technical protocols. So the authors try to take stock of the CRF test specificity. They report the results obtained after 100 micrograms o-CRF intravenous administration in 7 voluntary normal men.
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Arch Rehabil Res Clin Transl
December 2024
Department of Medicine, University of Maryland School of Medicine, Baltimore, MD.
Objective: To test the hypothesis that step count based on a virtual 2-minute step test (2MST) predicts cardiorespiratory fitness (CRF).
Design: Cross-sectional study.
Setting: Veteran Affairs Medical Centers participating in a randomized trial of functional exercise training delivered by videoconferencing.
J Appl Physiol (1985)
January 2025
Department of Neurology, University of Texas Southwestern Medical Center, Dallas, TX, USA.
High cardiorespiratory fitness (CRF) is associated with reduced cortical thinning and gray matter (GM) shrinkage in older adults. We investigated associations of CRF measured with peak oxygen consumption (V̇ O) with cortical thickness and GM volume across the adult lifespan. We hypothesized that higher CRF is associated with less cortical thinning and GM shrinkage across the adult lifespan, which is associated with better cognitive performance.
View Article and Find Full Text PDFDisabil Rehabil
January 2025
Caring Futures Institute, College of Nursing and Health Sciences, Flinders University, Adelaide, SA, Australia.
Purpose: To systematically review the evidence investigating the implementation of cardiorespiratory (CR) training in adults following a stroke and to understand how interventions are prescribed to address cardiorespiratory fitness (CRF).
Methods: Medline, CINAHL, EMBASE, EMCARE, Scopus, PEDro and ProQuest were searched from inception until January 2024. Inclusion criteria were studies that included adults following a stroke, investigated CR training interventions and used standardised CRF assessments.
J Am Coll Cardiol
January 2025
Mount Sinai Fuster Heart Hospital, Icahn School of Medicine at Mount Sinai, New York, New York, USA. Electronic address: https://twitter.com/DLBHATTMD.
Background: In patients with ST-segment elevation myocardial infarction (STEMI) and multivessel coronary artery disease, most but not all randomized trials have reported that complete revascularization (CR) offers advantages over culprit vessel-only revascularization. In addition, the optimal timing and assessment methods for CR remain undetermined.
Objectives: The purpose of this study was to identify the optimal revascularization strategy in patients with STEMI and multivessel disease, using a network meta-analysis of randomized controlled trials.
Introduction Cardiorespiratory fitness (CRF) is a key health indicator for assessing optimal physical function and overall well-being. Exploring the early impact of body mass index (BMI) and anthropometric measures on CRF in non-obese individuals is essential for identifying risk factors and guiding preventive strategies to address weight-related health challenges. This study aims to investigate the impact of BMI and anthropometric measures on CRF, focusing on maximal oxygen uptake (VO2max) and metabolic equivalents (METs) in non-obese adult males.
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