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Objective: to compare carbon dioxide and saline solution distension in diagnostic hysteroscopies with regards to patient discomfort and procedural time and in accordance with the instrument diameter (5 mm vs 3.5 mm). The secondary outcome was to evaluate the role of the patient age and the obstetrical history on perception of pain and procedural time.
Study Design: This is a prospective multicenter randomized study including 1982 patients that underwent office diagnostic hysteroscopy in: Policlinico Abano Terme, Università Cattolica del Sacro Cuore in Rome and Ente Ecclesiastico Ospedale Generale Regionale "F. Miulli" in Acquaviva delle Fonti. They were firstly randomized according to distension medium and secondly according to instrument diameter. Pain perception after the procedure was assessed by VAS (Visual Analogue Scale) score and procedural time was registered. Mann-Whitney U test was used to compare data.
Results: Lower pain score and procedural time were recorded with the employment of Carbon Dioxide (p < 001). Patient discomfort and procedural time were significantly influenced by the instrument diameter independent of the distension medium used, though in the subgroup where gas was employed VAS score after 1 min (VAS1) resulted lower compared to saline solution in both the traditional and mini-hysteroscopy procedures (p < 001).
Conclusion: Carbon dioxide and saline solution are both suitable distension media for outpatient diagnostic hysteroscopy; nonetheless, carbon dioxide confers advantages in terms of pain perception and procedural time.
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http://dx.doi.org/10.1016/j.ejogrb.2018.09.041 | DOI Listing |
Langmuir
December 2024
Department of Aeronautics and Astronautics, Kyushu University, Motooka 744, Nishi-Ku, Fukuoka 819-0395, Japan.
Despite the importance of the effect of subnanoscale roughness on contact line behavior, it is difficult to directly observe the local behavior of contact lines at the micro- and nanoscale, leaving significant gaps in our current understanding. In this research, we investigate contact line motions and their relationship with nanoscale surface topography using coherence scanning interferometry. Our experiments were conducted on the substrates with different wettability without changing nanoscale surface topography.
View Article and Find Full Text PDFMicrob Pathog
December 2024
Beijing Hospital of Traditional Chinese Medicine, Capital Medical University, Beijing, China; Beijing Institute of Chinese Medicine, Beijing, China; Beijing Key Laboratory of Basic Research with Traditional Chinese Medicine on Infectious Diseases, Beijing, China. Electronic address:
A striking characteristic of the human fungal pathogen Candida albicans is its ability to switch between budding yeast morphology and the filamentous form, facilitating its adaptation to changing host environments. The filamentous growth of C. albicans is mediated by various environmental factors, such as carbon dioxide (CO), N-acetylglucosamine (GlcNAc), serum, and high temperature.
View Article and Find Full Text PDFACS Appl Mater Interfaces
December 2024
College of Chemistry, Chemical Engineering and Materials Science, Soochow University, Suzhou 215123, Jiangsu, China.
Ruthenium dioxide (RuO) is one of the promising catalysts for the acidic oxygen evolution reaction (OER). However, designing RuO catalysts with good activity and stability remains a significant challenge. In this work, we propose the manganese (Mn)-doped RuO assembly as a catalyst for the OER with improved activity and stability.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
December 2024
School of Management, Sichuan Agricultural University, Chengdu, 611130, China.
Agricultural productivity remains pivotal to the sustenance of the economies and livelihoods of Sub-Saharan African (SSA) countries. However, the emerging threat of climate change poses a significant challenge to these agricultural-dependent economies. Sub-Saharan African countries are at risk of experiencing the severe effects of climate change on their agricultural productivity.
View Article and Find Full Text PDFEnviron Sci Pollut Res Int
December 2024
Department of Engineering, College of Engineering and Technology, University of Technology and Applied Sciences, Musandam, PC, 811, Oman.
Among the numerous residential appliances, window or split air conditioners are the most prevalent. The hydrochlorofluorocarbon and hydrofluorocarbon refrigerants used in those systems are causing a serious threat to the environment. In this study, R290-hydrofluoroolefin (HFO) mixtures are proposed as replacements for high-GWP substances (R410A and R22) in window air conditioning (WAC) units.
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