One prominent feature of adaptive cognition in humans is the ability to flexibly adjust to changing task demands. In this respect, context-specific proportion congruency (CSPC) effects describe the phenomenon that participants learn to adapt to contexts of frequently occurring conflicts even when the upcoming context cannot be anticipated. Here, we aim to provide evidence that such CSPC effects strongly depend on the affective valence of the context. Participants had to categorize pictures as animals versus humans (Experiment 1), words as male versus female (Experiment 2), and food pictures as depicting cold or hot dishes/beverages (Experiment 3). Stimuli were laterally presented to the left or right, creating Simon-like response interference. Half of the stimuli were of positive valence, half of negative valence with valence always being task-irrelevant. Positive or negative stimuli were associated with a high proportion of incongruent trials and a low proportion of congruent trials, respectively. In all three experiments, a CSPC effect was only significant when the high proportion of incongruent trials was associated with positive stimuli but reduced or even absent when the high proportion of incongruent trials was associated with negative stimuli. The findings further speak to the idea that it is the aversive nature of conflict stimuli that functions as a trigger for control adaptation. And such an unexpected aversive conflict signal looms larger when presented in a positive context than in a negative context. (PsycINFO Database Record (c) 2019 APA, all rights reserved).
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PLoS One
January 2025
Department of Crop Production and Landscape Management, Ebonyi State University, Abakaliki, Nigeria.
Background: Sweetpotato is a vegetatively propagated crop cultivated worldwide, predominantly in developing countries, valued for its adaptability, short growth cycle, and high productivity per unit land area. In most sub-Saharan African (SSA) countries, it is widely grown by smallholder farmers. Niger, Nigeria, and Benin have a huge diversity of sweetpotato accessions whose potential has not fully been explored to date.
View Article and Find Full Text PDFPLoS One
January 2025
Ministry of National Health Services, Regulations and Coordination, Islamabad, Pakistan.
Background: Pakistan has experienced a significant reduction in maternal mortality with a decline of 33 percent between 2006 and 2019. However, the country still grapples with a high number (186 per 100,000 live births) of maternal deaths each year. This study aims to identify socio-demographic and health system related factors associated with maternal mortality.
View Article and Find Full Text PDFHum Reprod
January 2025
Clinical Experimental Center, Jiangmen Engineering Technology Research Center of Clinical Biobank and Translational Research, Jiangmen Central Hospital, Jiangmen, China.
Study Question: What is the prevalence and trend of infertility among individuals of childbearing age at global, regional, and national levels by sex and socio-demographic index (SDI) across 21 regions and 204 countries and territories?
Summary Answer: Our findings reveal a growing prevalence of infertility among individuals aged 15-49 years worldwide from 1990 to 2021, with an expected continued increase through 2040.
What Is Known Already: Infertility is a persistent global reproductive health issue, leading to significant societal and health consequences. No study has specifically described the current prevalence of infertility, its secular trend, or the variations between regions or countries with different SDI levels.
Rheumatology (Oxford)
January 2025
Department of Rheumatology, Hospital Universitario La Paz-IdiPaz, Madrid, Spain.
Objectives: Giant cell arteritis (GCA) is a large/medium-vessel granulomatous vasculitis, and the PD-1/PD-L1 coinhibitory pathway seems to be implicated in its pathogenesis. CD4 T cells expressing high PD-1 levels, CD4+CXCR5-PD-1hi peripheral helper (Tph) and CD4+CXCR5+PD-1hi follicular helper T cells (Tfh), are key mediators of autoimmunity. Their frequencies are elevated in the peripheral blood of subjects with several autoimmune conditions but have not been investigated in GCA.
View Article and Find Full Text PDFJAMA Netw Open
January 2025
Department of Medicine, Cumming School of Medicine, University of Calgary, Calgary, Alberta, Canada.
Importance: People with kidney failure have a high risk of death and poor quality of life. Mortality risk prediction models may help them decide which form of treatment they prefer.
Objective: To systematically review the quality of existing mortality prediction models for people with kidney failure and assess whether they can be applied in clinical practice.
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