An Innovative Ventricular Assist Device Strategy as a Bridge-to-Recovery in an Infant with Glenn Physiology.

ASAIO J

From the Division of Pediatric Cardiothoracic Surgery, Department of Surgery, University of Tennessee Health Science Center, Le Bonheur Children's Hospital, Memphis, Tennessee.

Published: March 2020

AI Article Synopsis

  • Mechanical circulatory support for infants with single ventricle physiology poses challenges, but using a ventricular assist device (VAD) may offer benefits over traditional extracorporeal treatments.
  • A novel VAD approach effectively supported an infant with Glenn physiology who was in cardiogenic shock due to unspecified heart issues, maintaining systemic blood flow without relying on the existing circulation.
  • After seven days of VAD use, the patient showed significant recovery and was able to have the device removed, remaining healthy and free from the need for a transplant for 16 months afterwards.

Article Abstract

Mechanical circulatory support for infants with single ventricle physiology remains challenging. Utilization of a ventricular assist device (VAD) has potential advantages over extracorporeal circulatory membrane oxygenation. As such, VAD utilization in single ventricle patients with refractory heart failure continues to be explored. Herein, we describe a novel VAD strategy to support an infant with Glenn physiology who presented in cardiogenic shock related to myocardial depression of unknown etiology. This VAD configuration supported the systemic circulation independent of the Glenn circulation. Seven days of VAD support resulted in recovery of myocardial and end-organ function leading to VAD removal. The patient remains alive and free from transplantation 16 months post VAD explantation.

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Source
http://dx.doi.org/10.1097/MAT.0000000000000836DOI Listing

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