AI Article Synopsis
- Carvacrol has shown significant therapeutic potential in various in vitro studies, indicating its effectiveness against multiple diseases.
- A systematic review was conducted, analyzing studies from reputable databases, resulting in 31 relevant studies out of an initial 3,269.
- The identified properties of carvacrol include antimicrobial, anti-inflammatory, anticancer, antioxidant, and others, confirming its diverse pharmacological effects.
Article Abstract
Carvacrol has a high therapeutic potential, with in vitro studies showing promising results in different cellular models using a variety of methodological designs. Therefore, the objective of this study was to conduct a systematic review to analyze the pharmacological effects of carvacrol in in vitro studies. A comprehensive search of the literature was made using four databases: Science Direct, Scopus, MEDLINE-PubMed, and Web of Science using different combinations of the following keywords: carvacrol, drug therapy, therapeutic uses, in vitro study. The search of the databases was for studies conducted in the period up to and including September 2016. A total of 3,269 studies were initially identified, with only 31 meeting the inclusion criteria. The included studies contained a variety of in vitro models able to determine the properties of Carvacrol. The following properties of Carvacrol were identified: antimicrobial (7 studies), bactericidal (4), bactericidal and antifungal (1), antiinflammatory (4), anticancer (4), mutagenic (4), antioxidant (3), antifungal (3), antidepressant (1), as a modulator of nerve impulses (1) and an immunological modulator (1). The In vitro studies with Carvacrol included in this review showed a diversity of models and confirmed the therapeutic potential of this product in relation to several diseases.
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| http://dx.doi.org/10.2174/1381612824666181003123400 | DOI Listing |
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