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http://journals.plos.org/plosone/article?id=10.1371/journal.pone.0205289 | PLOS |
Plant Sci
January 2025
State Key Laboratory of Hybrid Rice, Key Laboratory for Research and Utilization of Heterosis in Indica Rice of the Ministry of Agriculture, Engineering Research Center for Plant Biotechology and Germplasm Utilization of the Ministry of Education, College of Life Science, Wuhan University, Wuhan 430072, China.
It is well known that activation of NMDA receptors can trigger long-term synaptic depression (LTD) and that a morphological correlate of this functional plasticity is spine retraction and elimination. Recent studies have led to the surprising conclusion that NMDA-induced spine shrinkage proceeds independently of ion flux and requires the initiation of protein synthesis, highlighting an unappreciated contribution of mRNA translation to non-ionotropic NMDAR signaling. Here we used NMDA-induced spine shrinkage in slices of mouse hippocampus as a readout to investigate this novel modality of synaptic transmission.
View Article and Find Full Text PDFEnviron Res
January 2025
Faculty of Engineering and Science, Western Norway University of Applied Sciences, Bergen, 5063, Norway.
This article has been retracted: please see Elsevier Policy on Article Withdrawal (https://www.elsevier.com/locate/withdrawalpolicy).
View Article and Find Full Text PDFInt J Biol Macromol
January 2025
Department of Medical Genetics, Zhongshan School of Medicine, Sun Yat-sen University, 510080 Guangzhou, China.
EMBO J
January 2025
Cambridge Institute for Medical Research, University of Cambridge, Cambridge, CB2 0XY, UK.
Biogenesis of membrane-bound organelles involves the synthesis, remodeling, and degradation of their constituent phospholipids. How these pathways regulate organelle size remains poorly understood. Here we demonstrate that a lipid-degradation pathway inhibits expansion of the endoplasmic reticulum (ER) membrane.
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