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The impact of ovulation-suppressing contraceptives on behavioral and functional difficulties in borderline personality disorder.
Neuropsychopharmacology
January 2025
Department of Gynecology and Obstetrics, Emory University, Atlanta, USA.
Borderline Personality Disorder (BPD) is characterized by rapidly shifting emotional, interpersonal, and behavioral symptoms, often co-morbid with mood and anxiety disorders. Females are more likely to be diagnosed with BPD than males and exhibit greater functional impairment. Hormonal fluctuations may influence the manifestation of BPD symptoms.
View Article and Find Full Text PDFNeural representation of sensorimotor features in language-motor areas during auditory and visual perception.
Commun Biol
January 2025
School of Psychology, Shenzhen University, Shenzhen, China.
Speech processing involves a complex interplay between sensory and motor systems in the brain, essential for early language development. Recent studies have extended this sensory-motor interaction to visual word processing, emphasizing the connection between reading and handwriting during literacy acquisition. Here we show how language-motor areas encode motoric and sensory features of language stimuli during auditory and visual perception, using functional magnetic resonance imaging (fMRI) combined with representational similarity analysis.
View Article and Find Full Text PDFAarskog-Scott syndrome: a clinical study based on a large series of 111 male patients with a pathogenic variant in and management recommendations.
J Med Genet
January 2025
Service de Génétique, Centre Hospitalier Régional Universitaire de Tours, Tours, France
Background: Aarskog-Scott syndrome (AAS) is a rare condition with multiple congenital anomalies, caused by hemizygote variants in the gene. Its description was based mostly on old case reports, in whom a molecular diagnosis was not always available, or on small series. The aim of this study was to better delineate the phenotype and the natural history of AAS and to provide clues for the diagnosis and the management of the patients.
View Article and Find Full Text PDFGlycosylation on extracellular vesicles and its detection strategy: Paving the way for clinical use.
Int J Biol Macromol
January 2025
The Affiliated Hospital of Qingdao University, Qingdao University, Qingdao 266071, China. Electronic address:
Extracellular vesicles (EVs) contain various glycans during their life cycle, from biogenesis to cellular recognition and uptake by recipient cells. EV glycosylation has substantial diagnostic significance in multiple health conditions, highlighting the necessity of determining an accurate glycosylation pattern for EVs from diverse biological fluids. Reliable and accessible glycan detection techniques help to elaborate the glycosylation-related functional alterations of specific proteins or lipids.
View Article and Find Full Text PDFAn exploration of the relationship between ineffective modes of mentalization and difficulties related to borderline personality disorder: A network approach.
J Affect Disord
January 2025
Research Department of Clinical, Educational & Health Psychology, University College London, UK; Anna Freud National Centre for Children and Families, London, UK.
Background: The mentalization-based perspective of Borderline Personality Disorder (BPD) underscores fluctuating interpersonal functionality, believed to arise from suboptimal mentalization modes, including hyper- and hypomentalizing. The connection between ineffective mentalizing and specific BPD challenges remains ambiguous. Network theory offers a unique means to investigate the hypothesis that distinct yet interconnected mental challenges ('symptoms') construct 'disorders' through their continuous mutual interactions.
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