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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6162119 | PMC |
| http://dx.doi.org/10.31486/toj.18.0011 | DOI Listing |
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Similar Publications
Use of LCP-Tacrolimus (LCPT) in Kidney Transplantation: A Delphi Consensus Survey of Expert Clinicians.
Ann Transplant
March 2024
Division of Nephrology and Department of Medicine, David Geffen School of Medicine, Los Angeles, CA, USA.
Article Synopsis
- LCPT (Envarsus XR®) is an extended-release tacrolimus used in kidney transplants, but there's a lack of clear guidelines on its dosing and use in new patients or those switching from other forms.
- A group of 12 experts used the Delphi method to create and refine consensus statements on LCPT use, achieving significant agreement on 18 out of 23 generated statements after two rounds of feedback.
- Key findings included that LCPT is recommended as a first-line option for new patients, especially African Americans and rapid metabolizers, and that conversion to LCPT is effective for mitigating neurological side effects from immediate-release tacrolimus.
The use of LCP-Tacrolimus (Envarsus XR) in simultaneous pancreas and kidney (SPK) transplant recipients.
Am J Surg
April 2020
Albert Einstein College of Medicine, Bronx, NY, USA; Montefiore-Einstein Center for Transplantation, Montefiore Medical Center, Bronx, NY, USA. Electronic address:
Background: Extended release LCP-tacrolimus (LCPT) allows once-daily dosing in transplant recipients. The improved bioavailability may be beneficial for simultaneous pancreas-kidney recipients (SPK).
Methods: This is a study of 39 SPK recipients on standard immediate-release tacrolimus (IR-TAC, n = 21) or LCPT (n = 18).
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