Until recently, Sri Lanka was not considered a country with endemic melioidosis. However, an increasing number of cases is being reported. National surveillance for melioidosis was instituted after 2008. A total of 250 culture-positive cases was recorded between 2006 and May 2017. Males predominated (71.6%). The age range was wide (2⁻92 years) reflecting a ubiquity of exposure. The majority (201/250, 80%) lived in rural areas. All provinces were affected. Case load increased during the two monsoonal periods (67%). There was representation of every population group including farmers ( = 44), housewives ( = 24), school children ( = 10), professionals ( = 5), businesspersons ( = 6), white-collar workers ( = 10) and blue-collar workers ( = 8). Diabetes was the predominant risk factor ( = 163, 65.2%). Clinical presentations included community-acquired sepsis and pneumonia, superficial and deep abscesses, and septic arthritis. Mortality was 20.4% (51/250). A majority ( = 212) of isolates belonged to the YLF (Yersinia-like fimbrial) clade but 38 were BTFC (-like flagellum and chemotaxis). A total of 108 isolates was genotyped and 46 sequence types (STs) were identified, 40 being novel. It is clear that melioidosis is endemic in Sri Lanka with a wide geographic and demographic distribution. There is an urgent need to extend surveillance of melioidosis to under-resourced parts of the country and to populations at high risk.
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| http://dx.doi.org/10.3390/tropicalmed3010022 | DOI Listing |
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