Objectives: The objective of this study is to examine efficacy of text message reminders and to educate and promote safe personal listening device (PLD) use in young adults.
Methods: Three hundred and eighty-seven urban college students from an urban university located in New York City, New York, participated in this pre- and postsurvey 6-month study (September 2016-March 2017). One hundred and ninety-eight students assigned to Group 1 (safe PLD use) received biweekly informative and humorous text reminders to encourage safe PLD use; 189 students assigned to Group 2 (controls) received monthly text messages related to the importance of their participation in the study with no mention of responsible PLD use. The Kruskal-Wallis test was used to analyze the pre- and postquestionnaire data; outcomes were considered significant at < 0.05.
Results: Participants who received text message reminders reported significant ([1] = 86.7, < 0.001) change in increasing responsible PLD use; no significant change was reported by controls ([1] = 0.002, = 0.96). Females assigned to Group 1 reported modified PLD use more ([1] = 6.7, < 0.01) than males, suggesting a gender effect. Participants who received the bi-weekly text reminders rated them as helpful in promoting responsible PLD use; participants assigned to the control group who did not receive biweekly text reminders indicated the reminders could have been helpful in promoting safe PLD use.
Conclusions: Text message reminders were reported and appear effective in motivating responsible PLD use in young adults.
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6149122 | PMC |
http://dx.doi.org/10.4103/jehp.jehp_106_18 | DOI Listing |
Toxicon
January 2025
Venom and Biotherapeutics Molecules Lab., Medical Biotechnology Department, Biotechnology Research Center, Pasteur Institute of Iran, Tehran, Iran. Electronic address:
Scorpion envenomation, especially from Hemiscorpius lepturus, poses a significant health risk, leading to considerable morbidity and mortality. The venom's major toxin, which includes phospholipase D (PLD), is responsible for various systemic complications. In prior studies, we identified a native phospholipase D (PLD) toxin as a key lethal factor in the venom of H.
View Article and Find Full Text PDFUnlabelled: The endocannabinoid (eCB) system regulates stress responsiveness and hypothalamic-pituitary-adrenal (HPA) axis activity. The enzyme -acyl phosphatidylethanolamine phospholipase-D (NAPE-PLD) is primarily responsible for the synthesis of the endocannabinoid signaling molecule anandamide (AEA) and other structurally related lipid signaling molecules known as -acylethanolamines (NAEs). However, little is known about how activity of this enzyme affects behavior.
View Article and Find Full Text PDFExp Mol Med
July 2024
Department of Pharmacy, Yonsei University, Incheon, 21983, Republic of Korea.
The development of chemoresistance is a major challenge in the treatment of several types of cancers in clinical settings. Stemness and chemoresistance are the chief causes of poor clinical outcomes. In this context, we hypothesized that understanding the signaling pathways responsible for chemoresistance in cancers is crucial for the development of novel targeted therapies to overcome drug resistance.
View Article and Find Full Text PDFACS Appl Mater Interfaces
July 2024
Laboratoire des Sciences des Procédés et des Matériaux (LSPM), CNRS, Université Sorbonne Paris Nord, 93430 Villetaneuse, France.
The control of local heterogeneities in metallic glasses (MGs) represents an emerging field to improve their plasticity, preventing the propagation of catastrophic shear bands (SBs) responsible for the macroscopically brittle failure. To date, a nanoengineered approach aimed at finely tuning local heterogeneities controlling SB nucleation and propagation is still missing, hindering the potential to develop MGs with large and tunable strength/ductility balance and controlled deformation behavior. In this work, we exploited the potential of pulsed laser deposition (PLD) to synthesize a novel class of crystal/glass ultrafine nanolaminates (U-NLs) in which a ∼4 nm thick crystalline Al separates 6 and 9 nm thick ZrCu glass nanolayers, while reporting a high density of sharp interfaces and large chemical intermixing.
View Article and Find Full Text PDFBMC Genomics
June 2024
Cell and Molecular Biology and Trait Engineering, International Crops Research Institute for the Semi-Arid Tropics (ICRISAT), Hyderabad, Patancheru, Telangana, 502324, India.
Background: Phospholipases constitute a diverse category of enzymes responsible for the breakdown of phospholipids. Their involvement in signal transduction with a pivotal role in plant development and stress responses is well documented.
Results: In the present investigation, a thorough genome-wide analysis revealed that the pearl millet genome contains at least 44 phospholipase genes distributed across its 7 chromosomes, with chromosome one harbouring the highest number of these genes.
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