Background: Many hospitals use predictive scores to identify a person's risk of inpatient falls, pressure injury and malnutrition despite evidence of limited predictive accuracy.
Aim: To examine whether we could improve predictive accuracy by generating a score combining all components of currently used tools.
Methods: We performed a retrospective, cross-validation study in a single sub-acute (geriatrics and rehabilitation) hospital, extracting data regarding hospital risk scores, and incidence of falls, pressure injury and malnutrition from January 2014 to June 2016. The sample was randomly halved into training and testing data sets. For each harm outcome, model fit was examined using area under receiver operating characteristic curves (AUC) and proportions of people reclassified based on a combined score were calculated. Secondary analyses explored the predictive performance of individual question-responses.
Results: Data were available for 4487 admissions (median age 83.0 years). A total of 667 (15%) people had at least one fall, 499 (11%) had at least one pressure injury and 20 (0.4%) malnutrition. The currently used tools had, at best, moderate ability to predict risk of harm outcomes (AUC 0.56-0.73). Testing of the combined score models resulted in minimal change in AUC (<5.1%) and did not add value to risk category reclassification. Most of the predictive ability of the currently used tools relied on the performance of two individual question-responses.
Conclusion: Combining scores or reducing to two-item question-responses did little to change predictive accuracy. This study highlights the limitations of hospital harm predictive scores and emphasises the importance of rigorous testing of predictive scores.
Download full-text PDF |
Source |
---|---|
http://dx.doi.org/10.1111/imj.14121 | DOI Listing |
Pediatr Res
January 2025
Neonatal Intensive Care Unit, University Hospital of Modena, Via del Pozzo, 41124, Modena, Italy.
Background: Our aim was to develop a quantitative model for immediately estimating the risk of death and/or brain injury in late-onset sepsis (LOS) in preterm infants, based on objective and measurable data available at the time sepsis is first suspected (i.e., time of blood culture collection).
View Article and Find Full Text PDFPLoS One
January 2025
Department of Pain Medicine, Aichi Medical University, Nagakute, Aichi, Japan.
Background: Lowering barometric pressure (LP) can exacerbate neuropathic pain. However, animal studies in this field are limited to a few conditions. Furthermore, although sympathetic involvement has been reported as a possible mechanism, whether the sympathetic nervous system is involved in the hypothalamic-pituitary-adrenal (HPA) axis remains unknown.
View Article and Find Full Text PDFACS Nano
January 2025
Guangdong Provincial Key Laboratory of Reproductive Medicine, Guangdong Provincial Clinical Research Center for Obstetrical and Gynecological Diseases, Department of Gynecology & Obstetrics, Reproductive Medicine Center, The First Affiliated Hospital, Sun Yat-sen University, Guangzhou 510080, PR China.
Regeneration of the injured endometrium, particularly the functional layer, is crucial for the prevention of uterine infertility. At present, clinical treatment using sodium hyaluronate hydrogel injection is limited by its relatively low fluidity, short-term retention, and insufficient bioactive ingredients, so it is necessary to develop an advanced healing-promoting hydrogel. The modulation of the microenvironment by presents a bioactive component that can facilitate the regeneration of the functional layer.
View Article and Find Full Text PDFAm J Transl Res
December 2024
Department of Neurosurgery, Baotou Central Hospital Baotou 014040, Inner Mongolia Autonomous Region, China.
Objective: To identify factors influencing neurological prognosis following traumatic brain injury (TBI) and to analyze the role of brain tissue oxygen pressure (PbtO) monitoring in prognostication.
Methods: In this case-control study, medical records of 412 individuals diagnosed with TBI were thoroughly examined and analyzed. The patients were divided into two groups based on their prognosis at three months post-injury: Good Prognosis (n = 321) and Poor Prognosis (n = 91).
Am J Transl Res
December 2024
Department of Urinary Surgery, Jiashan County Chinese Medicine Hospital Jiaxing, Zhejiang, China.
Objective: To explore the effects and safety of the flexible vacuum-assisted ureteral access sheath combined with a flexible ureteroscope for the treatment of large renal stones over 3 cm.
Methods: In this retrospective study, 122 patients with kidney stones (stone diameter ≥ 3 cm) admitted to our hospital from January 2018 to December 2022 were selected as the study subjects. According to different surgical methods, these patients were divided into an observation group and a control group, with 61 cases in each group.
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!