The purpose of this study was to evaluate the dosimetric variation among six non-beam-matched Varian linacs using different techniques for the same plans. Six non-beam-matched Varian machines, comprising two Clinac iX, two 600 C/D (Unique), and two True Beam Tx photon 6 MV X-ray devices were acquired. Sixty patients with of head and neck (H&N; 30) and pelvic (30) treatment sites were chosen. For all 60 patients, three-dimensional conformal radiotherapy (3DCRT), intensity-modulated radiotherapy (IMRT), and volumetric-modulated radiotherapy (VMAT) plans were generated for the Clinac iX-1 device; all plans were migrated to the remaining machines, using the eclipse treatment planning system without any modification. The dosimetric variation among the six machines for each target volume and organ at risk was recorded and analyzed. In H&N cases, the maximum variation among the six machines with 3DCRT, IMRT, and VMAT was 2.57%, 2.6%, and 2.6%, respectively. In pelvic cases, the maximum variation among the six machines with 3DCRT, IMRT, and VMAT was 2.2%, 1.95%, and 2.05%, respectively. Our overall results show that dosimetric variation, while interchanging the plans among the six machines at phantom and patient levels, remains within the limits of clinical acceptability. The noted variation was not correlated with any of these treatment techniques: 3DCRT, IMRT, or VMAT.
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http://dx.doi.org/10.1007/s12194-018-0480-3 | DOI Listing |
J Appl Clin Med Phys
December 2024
Department of Radiation Oncology, Taussig Cancer Institute, Cleveland Clinic, Cleveland, Ohio, USA.
Background: Whole bladder irradiation is an organ preservation treatment approach for muscle-invasive bladder cancer (MIBC). Conventional planning margins, typically 15-20 mm, increase normal tissue toxicity and limit possible dose escalation.
Purpose: The study aimed to develop a patient-specific adaptive margin recipe for whole bladder irradiation to minimize the planning target volume (PTV) while preserving adequate dose coverage.
J Appl Clin Med Phys
December 2024
Department of Radiation Oncology, Virginia Commonwealth University, Richmond, Virginia, USA.
Purpose: This study assesses a novel, automated dose accumulation process during MR-guided online adaptive radiotherapy (MRgART) for prostate cancer, focusing on inter-fractional anatomical changes and discrepancies between delivered and planned doses.
Methods: A retrospective analysis was conducted on seven prostate cancer patients treated with a five-fraction stereotactic body radiation therapy (SBRT), using a 0.35T MRIdian MR-LINAC system.
Med Phys
December 2024
Department of Physics, The Verspeeten Family Cancer Centre, London, Ontario, Canada.
Background: Stereotactic arrythmia radioablation (STAR) is a noninvasive technique to treat ventricular tachycardia (VT). Management of cardiorespiratory motion plays an essential role in VT-STAR treatments to improve treatment outcomes by reducing positional uncertainties and increasing dose conformality. Use of an electrocardiogram (ECG) signal, acquired in real-time, as a surrogate to gate the beam has the potential to fulfil that intent.
View Article and Find Full Text PDFRadiat Oncol
December 2024
Department of Radiation Oncology, Shanghai Proton and Heavy Ion Center, Fudan University Cancer Hospital, NO. 4365 Kang Xin Road, Shanghai, 201315, China.
Background And Purpose: This study evaluates the dosimetric impact of tumor matching (TM) and bone matching (BM) in carbon ion radiotherapy for locally advanced non-small cell lung cancer.
Materials And Methods: Forty patients diagnosed with locally advanced non-small cell lung cancer were included in this study. TM and BM techniques were employed for recalculation based on re-evaluation computed tomography (CT) images of the patients, resulting in the generation of dose distributions: Plan-T and Plan-B, respectively.
J Appl Clin Med Phys
December 2024
Department of Radiation Oncology, Fudan University Shanghai Cancer Center, Shanghai, China.
Background: Immobilization devices are essential for maintaining accurate and repeatable patient positioning in radiotherapy. This study aimed to evaluate the setup errors and dosimetric deviation induced by the deformation of immobilization devices in thoracic cancer radiotherapy using CT-linac.
Materials And Methods: A retrospective analysis was conducted on 40 thoracic cancer patients who underwent radiotherapy, using vacuum cushion (VC) and thermoplastic mask (TM) for immobilization.
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