Gastroenterology
Department of Basic Science Education, Virginia Tech Carilion School of Medicine, Roanoke, Virginia.
Published: July 2019
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http://dx.doi.org/10.1053/j.gastro.2018.09.042 | DOI Listing |
Rev Med Liege
March 2025
Service de Gastro-entérologie, Hépatologie et Oncologie digestive, CHU Liège, Belgique.
Crohn's disease is a chronic inflammatory bowel disease that can lead to fibrostenotic complications. These strictures result from an imbalance between inflammation and excessive healing, leading to an abnormal accumulation of extracellular matrix and a progressive thickening of the intestinal wall. To date, no specific treatment is available to prevent or reverse intestinal fibrosis.
View Article and Find Full Text PDFFront Pharmacol
February 2025
Department of Pediatric Gastroenterology and Hepatology and nutrition, University Hospitals Leuven, KU Leuven, Leuven, Belgium.
Introduction: Myositis is a rare extra-intestinal presentation in patients with inflammatory bowel diseases (IBD), and its occurrence has only been described in a few case reports. However, it is essential to consider other potential causes as patients with IBD are more susceptible to infections due to their immunocompromised status, which may also be exacerbated by immunosuppressive drugs contributing to myositis. Our case highlights the complexity and challenges in diagnosing and managing myositis in patients with IBD as well as a review of the literature.
View Article and Find Full Text PDFJ Crohns Colitis
March 2025
Takeda Pharmaceuticals, Inc., Cambridge, MA, USA (at the time of the analyses).
Inflammatory bowel diseases (IBD), Crohn's disease (CD), and ulcerative colitis (UC) are lifelong chronic, relapsing and remitting conditions that culminate in disease progression in many patients. Effective management of CD and UC requires consideration of both short and long-term treatment outcomes. Historically, short-term outcomes such as clinical and endoscopic remission and symptom relief have been evaluated in clinical trials.
View Article and Find Full Text PDFPLoS One
March 2025
Department of Gastroenterology, The Affiliated Hospital of Southwest Medical University, Luzhou, China.
Background: Observational studies have shown that ocular manifestations of inflammatory bowel disease (IBD) are common extraintinal manifestations, among which iridocyclitis, scleritis and episcleritis are the most common. However, whether there is a causal relationship between the two is unclear. The purpose of this study was to evaluate the causality of IBD on ocular manifestations using the mendelian randomization (MR) analysis.
View Article and Find Full Text PDFIntroduction Video Capsule Endoscopy (VCE) is a valuable non-invasive diagnostic tool for gastrointestinal disorders, but it carries a risk of capsule retention and subsequent bowel obstruction. The aim of the present study was to examine the manifestations, diagnostic approaches, treatment modalities, and outcome of patients with bowel obstruction due to VCE. Methods A comprehensive search was conducted in PubMed/Medline, EMBASE, Cochrane and Scopus databases focusing on intestinal obstruction post VCE.
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