Meningococcal infection remains a leading cause of morbidity and mortality. Based on the sequence of pathophysiological mechanisms and the agent and host factors, a wide spectrum of presentations may be seen. Here we report a non-fatal case of fulminant form of meningococcemia beginning as food poisoning complicated with shock I degree due to partially adrenal hemorrhage in Caucasian adult male.
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accumulate in large organs during meningococcal sepsis.
Front Cell Infect Microbiol
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Department of Medical Biochemistry, Oslo University Hospital, Oslo, Norway.
Background: (Nm) is the cause of epidemic meningitis and fulminant meningococcal septicemia. The clinical presentations and outcome of meningococcal septic shock is closely related to the circulating levels of lipopolysaccharides (LPS) and of DNA (Nm DNA). We have previously explored the distribution of Nm DNA in tissues from large organs of patients dying of meningococcal septic shock and in a porcine meningococcal septic shock model.
View Article and Find Full Text PDF[Analysis of fatal outcomes of meningococcal infection in adults].
Ter Arkh
December 2022
Kirov Military Medical Academy.
Clinical characteristics and pathomorphological manifestations in 69 patients aged 18 to 86 years with a fatal outcome of the disease were examined in order to analyze the causes of severe course and high mortality of generalized forms meningococcal infection. It was found that the main clinical form was meningococcemia (90%), in the majority in combination with meningitis (52%). The fulminant course in 77% of patients with meningococcal sepsis manifested itself as a sudden onset, rapid development of typical symptoms.
View Article and Find Full Text PDFMeningococcaemia In Children-An Under Recognized Public Health Problem In Pakistan.
J Ayub Med Coll Abbottabad
November 2022
Department of Paediatrics, Ayub Medical Teaching Institute, Abbottabad, Pakistan.
Background: Meningococcaemia is a serious bacterial disease caused by Neisseria meningitidis resulting in septicaemia and meningitis in previously well individuals and is associated with serious consequences including mortality. As the data from our region is scarce, the study was conducted with an aim to highlight the disease manifestations and outcomes so that appropriate interventions are devised.
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Invasive meningococcal disease persists as a fulminant disorder worldwide. Although cases caused by Neisseria meningitidis serogroup X (MenX) occur infrequently, outbreaks have been reported in countries in Africa in recent decades. We report 2 cases of MenX invasive meningococcal disease in São Paulo, Brazil, in 2021 and 2022, during the COVID-19 pandemic.
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