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The association among individual gray matter volume of frontal-limbic circuitry, fatigue susceptibility, and comorbid neuropsychiatric symptoms following COVID-19.
Neuroimage
January 2025
Department of Medical Imaging, the First Affiliated Hospital of Xi'an Jiaotong University, Xi'an, Shaanxi Province, China. Electronic address:
Article Synopsis
- The study investigates the neurobiological factors that make individuals susceptible to fatigue after a mild COVID-19 infection, aiming to understand the link between brain structure and post-COVID neuropsychiatric symptoms.
- Researchers used neuropsychiatric assessments and MRI scans on individuals who had COVID-19 and a control group to analyze brain regions related to fatigue.
- Results indicate that specific brain areas, particularly the right dorsolateral prefrontal cortex, are linked to fatigue severity and can predict ongoing fatigue symptoms months after the infection, shedding light on the neural underpinnings of post-COVID conditions.
Background: Mass disasters, whether natural or human-made, pose significant public health challenges, with some individuals demonstrating resilience, whereas others experience persistent emotional distress that may meet diagnostic criteria for mental health disorders. We explored key risk factors for distress following the October 7, 2023, Hamas attacks on Israel, focusing on trauma exposure, gender, and event centrality.
Method: A longitudinal study design was used, assessing posttraumatic distress (PTSD), depression, generalized anxiety, event centrality, and functioning at approximately three (T1; n=858) and seven (T2, n=509) months post-attack.
Predictors of dilation difficulty in gender-affirming vaginoplasty.
J Plast Reconstr Aesthet Surg
November 2024
Division of Plastic and Reconstructive Surgery, Icahn School of Medicine at Mount Sinai, New York, NY, USA; Mount Sinai Center for Transgender Medicine and Surgery, New York, NY, USA. Electronic address:
A necessary component of postoperative care in gender-affirming vaginoplasty is the dilation of the neovaginal canal. Difficulty with dilation can cause patient pain and distress, often decreasing compliance and leading to partial or complete closure of the neovaginal canal. This study sought to evaluate the sociodemographic, operative, and comorbid characteristics that contribute to patient difficulty with neovaginal dilation.
View Article and Find Full Text PDFExamining Cough's Role and Relief Strategies in Interstitial Lung Disease.
J Clin Med
January 2025
Corewell Health, Grand Rapids, MI 49503, USA.
Chronic cough is a distressing and prevalent symptom in interstitial lung disease (ILD), significantly impairing quality of life (QoL) and contributing to disease progression, particularly in idiopathic pulmonary fibrosis (IPF). It is associated with physical discomfort, psychological distress, and social isolation and is often refractory to conventional therapies. The pathophysiology of cough in ILD is complex and multifactorial, involving neural hypersensitivity, structural lung changes, inflammatory processes, and comorbid conditions such as gastroesophageal reflux disease (GERD).
View Article and Find Full Text PDFSexual function and related predictors in male with multiple sclerosis and neuromyelitis optica spectrum disorder: a case-control study.
J Sex Med
December 2024
Isfahan Neurosciences Research Center, Isfahan University of Medical Sciences, 81839-83434 Isfahan, Iran.
Background: Sexual dysfunction (SF) is a prevalent and distressing comorbidity in males with multiple sclerosis (MwMS) and neuromyelitis optica spectrum disorder (MwNMOSD).
Aims: This study aimed to assess the SF in MwMS and MwNMOSD in comparison to male healthy controls (HCs) and identify its associated predictors.
Methods: This case-control study was conducted from February 2023 to January 2024 at the MS clinic of Kashani Hospital, Isfahan, Iran.
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