AI Article Synopsis
- Antibiotic resistance poses a significant threat to public health, compromising the effectiveness of existing antibiotics and leading to higher mortality rates and economic costs.
- Rapid and precise diagnostics are essential for identifying bacterial pathogens and understanding their antibiotic resistance to tackle this crisis.
- Recent advancements in quantitative and synthetic biology are being explored to enhance the diagnosis and treatment strategies for resistant bacterial infections.
Article Abstract
Antibiotic resistance is one of the biggest threats to public health. The rapid emergence of resistant bacterial pathogens endangers the efficacy of current antibiotics and has led to increasing mortality and economic burden. This crisis calls for more rapid and accurate diagnosis to detect and identify pathogens, as well as to characterize their response to antibiotics. Building on this foundation, treatment options also need to be improved to use current antibiotics more effectively and develop alternative strategies that complement the use of antibiotics. We here review recent developments in diagnosis and treatment of bacterial pathogens with a focus on quantitative biology and synthetic biology approaches.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6152938 | PMC |
| http://dx.doi.org/10.1016/j.cobme.2017.10.007 | DOI Listing |
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