We have recently demonstrated that protein kinase C (PKC) promotes a stem-like, tumor-initiating cell phenotype in -driven lung adenocarcinoma by activating a novel ELF3-NOTCH3 signaling axis. Combined PKC and NOTCH inhibition was identified as a novel strategy for the treatment of -driven lung adenocarcinoma.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6154840 | PMC |
| http://dx.doi.org/10.1080/23723556.2016.1190886 | DOI Listing |
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