Phenolics and eudesmanolide from aged common sage exudate with sugar.

Nineteen compounds including one new flavanone were isolated from the juice of aged common sage exudate with sugar (ACSE). The isolated compounds were identified by NMR and MS analyses as levodopa methyl ester (), 3,4-dihydroxybenzoic acid (), ()-8-hydroxy-4-hydroxy-phenylpropanoic acid (), 4-hydroxybenzoic acid ethyl ester (), -caffeic acid (), -caffeic acid (), esculetin (), ()-8-hydroxy-3,4-dihydroxy-phenylpropanoic acid ethyl ester (), -rosmarinic acid (), -rosmarinic acid (), -rosmarinic acid methyl ester (), 6-methoxy-7,8,3',5'-tetrahydroxyflavanone (), nepetin (), -caffeic acid ethyl ester (), luteolin (), -caffeic acid ethyl ester (), 6-methoxynaringenin (), 1α-acetoxy-2-oxo-eudesman-3,7(11)-dien-8β,12-olide (), and hispidulin (). Compound was isolated for the first time from nature and seven compounds (, , , , , , and ) were newly identified from common sage. Of them, 15 isolated phenolic compounds (-, -, -, , and ) were detected in ACSE juice, while only was detected in the fresh common sage.