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The mung bean () is an important food crop with preventative effects against human diseases. The anti-allergic activities of mung bean sprouts of different lengths were evaluated by assaying antipruritic activity and hyaluronidase inhibitory effects. After 48 h of growth, sprouts were determined to have the best activity and extracted with petroleum (PeF), ethyl acetate (EaF), and n-butanol (nBF). The active EaF extracts were further assayed for effects on compound 48/80-induced mast cell degranulation and histamine release, as well as the anti-dinitrophenyl (DNP) IgE-induced passive cutaneous anaphylaxis (PCA) reaction. The main chemical constituents were further analyzed by UV spectrophotometry and high-performance liquid chromatography with tandem mass spectrometric detection (LC/MS/MS). EaF significantly protected against compound 48/80-induced mast cell degranulation and histamine release, and PCA. Flavonoids were determined to be the main contributors to the anti-allergic activity of the EaF extracts.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6049181 | PMC |
| http://dx.doi.org/10.1007/s10068-016-0077-8 | DOI Listing |
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