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Background: Gastrointestinal stromal tumors (GISTs) are relatively rare, accounting for approximately 0.1-3% of all gastrointestinal tumors. Their incidence is higher in individuals aged 50 to 70 years, with an equal gender distribution.
View Article and Find Full Text PDFProton Pump Inhibitors for Inducing and Maintaining Remission in Eosinophilic Esophagitis: An Updated Systematic Review and Meta-Analysis.
Clin Gastroenterol Hepatol
March 2025
Centro de Investigación Biomédica en Red Enfermedades Hepáticas y Digestivas (CIBEREHD), Toledo, Spain; Instituto de Investigación Sanitaria de Castilla-La Mancha (IDISCAM), 45004 Toledo, Spain; Instituto de Investigación Sanitaria Princesa, Madrid, Spain; Research Unit Complejo Hospitalario La Mancha Centro, Alcázar de San Juan, Spain.
Background & Aims: Proton pump inhibitor (PPI) therapy results in clinical and histological remission in approximately 50% of eosinophilic esophagitis (EoE) patients. We aimed to systematically update this topic due to cumulative data from pediatric/adult populations in wider geographical settings.
Methods: A search in MEDLINE, EMBASE, and SCOPUS databases was performed.
Vonoprazan in Management of Refractory Gastroesophageal Reflux Disease: An Indian Expert Group Consensus Statements.
J Assoc Physicians India
March 2025
Assistant Professor, Department of Gastroenterology, Institute of Medical Sciences, Banaras Hindu University, Varanasi, Uttar Pradesh, India.
Background: Approximately, 40% of gastroesophageal reflux disease (GERD) patients experience insufficient symptom relief from proton-pump inhibitors (PPI), resulting in PPI-refractory GERD (rGERD).
Objective: To review the existing literature and develop an Indian expert group consensus statement on the place of vonoprazan in the management of rGERD.
Materials And Methods: A panel of 35 leading Indian gastroenterologists extensively reviewed the literature to develop consensus statements for the management of rGERD in Indian patients, with a focus on the newly available potassium-competitive acid blocker (P-CAB), vonoprazan.
Role of Meditation as Adjuvant Therapy on Gastrointestinal Quality of Life among Individuals with Functional Dyspepsia in an Outpatient Setting: A Randomized Pilot Trial.
J Assoc Physicians India
March 2025
Professor, Department of Medicine, All India Institute of Medical Sciences (AIIMS), Rishikesh, Uttarakhand, India, Orcid: https://orcid.org/0000-0001-6336-5179.
Background: Functional dyspepsia (FD) is one of the most common reasons for medical visits. Patients with FD incur large direct and indirect expenditures and may have significant financial burdens that affect quality of life. Our study aimed to assess the effectiveness of meditation as an adjuvant to the standard treatment in individuals diagnosed with FD.
View Article and Find Full Text PDFThe Effect of Type of Sedation or Lack of It on Wireless Esophageal pH Capsule Test Results.
Neurogastroenterol Motil
March 2025
Division of Gastroenterology and Hepatology, MetroHealth Medical Center, Case Western Reserve University, Cleveland, Ohio, USA.
Introduction: Wireless esophageal pH monitoring is used to diagnose gastroesophageal reflux disease in patients with heartburn. Current studies are conflicting on the effect of sedation on acid reflux. The aim of our study was to determine if the type of sedation used during endoscopy or lack of it affects the first day of esophageal acid exposure results as compared to the second day.
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