New 18(4→3)-Abietanoids from .

Molecules

State Key Laboratory of Bioactive Substance and Function of Natural Medicines, Institute of Materia Medica, Chinese Academy of Medical Sciences and Peking Union Medical College, Beijing 100050, China.

Published: September 2018

Three 18(4→3)-abietanoids, a new natural product and two new compounds, named tripordolides A⁻C (⁻), were isolated from the leaves of Their structures were elucidated on the basis of their spectroscopic analysis, and the absolute configuration of compounds was confirmed by CD and X-ray crystallographic analysis using anomalous scattering of Cu α radiation. Compounds and showed moderate inhibitory activities against NO production in lipopolysaccharide-induced (LPS) RAW 264.7 macrophages in vitro.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6222710PMC
http://dx.doi.org/10.3390/molecules23102467DOI Listing

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