A 66-year-old man presented with a grayish 1mm macule on the left cheek. Dermatoscopic examination revealed annular-granular structures partially surrounding a single follicular ostium. Histopathologic examination demonstrated atypical, confluent single melanocytes at the basal layer with nesting, crowding, and upward migration descending along the hair follicle, consistent with the diagnosis of lentigo maligna (LM). This case presents evidence in support of the Schiffner progression model for LMs, starting with asymmetric pigmented follicular openings composed of annular-granular structures, which later coalesce into gray to dark black/brown streaks, and then form pseudo-networks or rhomboidal structures. The finding of annular-granular structures partially surrounding a single hair follicle may be the earliest recognizable dermatoscopic feature of an LM and may help clinicians diagnose facial LMs earlier.
Download full-text PDF |
Source |
|---|
Publication Analysis
Top Keywords
Similar Publications
Zoom-in Dermoscopy for Facial Tumors.
Diagnostics (Basel)
January 2025
Dermatology Unit, Department of Medical, Surgical and Neurological Sciences, University of Siena, 51300 Siena, Italy.
: Facial lesions, including lentigo maligna and lentigo maligna melanoma (LM/LMM), both malignant, present significant diagnostic challenges due to their clinical similarity to benign conditions. Although standard dermoscopy is a well-established tool for diagnosis, its inability to reveal cellular-level details highlights the necessity of new magnified techniques. This study aimed to assess the role of standard dermoscopy, high-magnification dermoscopy, and fluorescence-advanced videodermatoscopy (FAV) in diagnosing LM/LMM and differentiating them from benign facial lesions.
View Article and Find Full Text PDFAmelanotic/hypomelanotic lentigo maligna: Dermoscopic and confocal features predicting diagnosis.
J Eur Acad Dermatol Venereol
February 2023
Department of Medical, Surgical and Neurological Science, Dermatology Section, University of Siena, S. Maria alle Scotte Hospital, Siena, Italy.
Background: Amelanotic/hypomelanotic lentigo maligna and lentigo maligna melanoma (AHLM/LMM) may be very difficult to diagnose at an early stage.
Objectives: To quantify the predictive value of dermoscopic and reflectance confocal microscopy (RCM) features for AHLM/LMM.
Methods: Dermoscopic and RCM images of histopathologically diagnosed AHLM/LMM, amelanotic/hypomelanotic benign lesions (AHBL), and amelanotic/hypomelanotic basal and squamous cell carcinomas (AHBCC/AHSCC) of the head and neck from consecutive patients were retrospectively collected and blindly evaluated by three observers to assess presence or absence of dermoscopic and RCM criteria.
Flat scalp melanoma dermoscopic and reflectance confocal microscopy features correspond to histopathologic type and lesion location.
J Eur Acad Dermatol Venereol
August 2021
Department of Dermatology, University of Modena and Reggio Emilia, Modena, Italy.
Background: Dermoscopy and Reflectance Confocal Microscopy (RCM) features of scalp melanoma according to lesion location and histopathology have not been fully investigated.
Objectives: To reveal dermoscopic and RCM features of scalp melanoma according to lesion location and histopathology.
Methods: We retrospectively retrieved images of suspicious, atypical excised, flat melanocytic lesions of the scalp, assessed on dermoscopy and RCM at five centres, from June 2007 to April 2020.
Resonant phenomena and mechanism in vibrated granular systems.
Phys Rev E
March 2020
Institute of Acoustics and Key Laboratory of Modern Acoustics of Ministry of Education, Nanjing University, Nanjing 210093, China.
We were motivated to perform this research by the investigation of Brownian motors in excited granular materials converting the chaotic motion of granules into the oriented motion of motors. We conducted experimental studies to explore the horizontal motion of granules in vertically vibrated annular granular systems, including mixed and pure granular systems with an asymmetrical periodic structure on the bottom. The variations of the horizontal granular flow caused by the height, vibrating parameters, and mixing ratio were described in detail.
View Article and Find Full Text PDFDermoscopy findings of a one mm lentigo maligna.
Dermatol Online J
September 2018
Department of Dermatology, University of Minnesota, Minneapolis, Minnesota Department of Dermatology, Minneapolis Veterans Affairs Health Care System, Minneapolis, Minnesota Department of Medicine, University of Minnesota, Minneapolis, Minnesota Department of Medicine, Minneapolis Veterans Affairs Health Care System, Minneapolis, Minnesota.
A 66-year-old man presented with a grayish 1mm macule on the left cheek. Dermatoscopic examination revealed annular-granular structures partially surrounding a single follicular ostium. Histopathologic examination demonstrated atypical, confluent single melanocytes at the basal layer with nesting, crowding, and upward migration descending along the hair follicle, consistent with the diagnosis of lentigo maligna (LM).
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!