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| http://dx.doi.org/10.1111/bcp.13758 | DOI Listing |
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Benchmarking antimicrobial use to antimicrobial resistance: a comparative study of two hospitals using current National Healthcare Safety Network (NHSN) metrics.
Infect Control Hosp Epidemiol
January 2025
Center for Health Equity and Innovation, Cook County Health, Chicago, IL, USA.
Objective: We aimed to determine whether benchmarking antimicrobial use (AU) to antimicrobial resistance (AR) using select AU/AR ratios is more informative than AU metrics in isolation.
Design: We retrospectively measured AU (antimicrobial therapy days per 1,000 days present) and AU/AR ratios (specific antimicrobial therapy days per corresponding AR event) in two hospitals during 2020 through 2022. We then had antimicrobial stewardship committee members evaluate each AU and corresponding AU/AR value and indicate whether they believed it represented potential overuse, appropriate use, or potential underuse of the antimicrobials, or whether they could not provide an assessment.
Intensive Care Unit Admissions Among Persons With Dementia: Overuse or Underuse?
J Am Geriatr Soc
January 2025
Lady Davis Institute for Medical Research, Jewish General Hospital, Montreal, Quebec, Canada.
Cesarean section in Suriname using robson classification: a two-year nationwide cross-sectional study on rates, risk factors and perinatal outcomes of cesarean section.
BMC Pregnancy Childbirth
January 2025
Department of Obstetrics, Division Women and Baby, Birth Centre Wilhelmina's Children Hospital, University Medical Centre Utrecht, Utrecht University, UMC Utrecht, 3508 AB, Utrecht, Postbus 85090, the Netherlands.
Background: Optimizing CS performance is a global health priority, given the maternal and perinatal morbidity and mortality associated with both underuse and overuse. This study aims to (1) determine the facility-based CS rate in Suriname and explore which women are most likely to undergo a CS and (2) classify all CS by the WHO Robson classification and analyze the perinatal outcomes.
Methods: An observational, cross-sectional study in Suriname, using nationwide birth registry data that included all hospital births in 2020 and 2021 (≥ 27 weeks of gestation).
Social Relationships of Captive Bachelor Przewalski's Horses and Their Effect on Daily Activity and Space Use.
Animals (Basel)
December 2024
Department of Biology, University of Saskatchewan, 112 Science Place, Saskatoon, SK S7N 5E2, Canada.
Understanding social relationships in at-risk species held in captivity is vital for their welfare and potential reintroduction. In social species like the Przewalski's horse (), daily time allocation and space use may be influenced by social structure and, in turn, reflect welfare. Here, we identify social relationships, time budgets, and spatial distribution of a group of nine older (aged 6-21 years) male Przewalski's horses living in a non-breeding (bachelor) group.
View Article and Find Full Text PDFA randomized clinical study to evaluate the possible antifibrotic effect of zinc sulfate in chronic HCV patient receiving direct-acting anti-viral therapy.
Inflammopharmacology
January 2025
Department of Clinical Pharmacy, Faculty of Pharmacy, Tanta University, El-Gharbia Government, Tanta, Egypt.
Objective: This study aimed to assess the potential antifibrotic impact of zinc sulfate in chronic Hepatitis C Virus (HCV) patients receiving direct-acting antiviral therapy.
Methods: This randomized controlled study included 50 chronic HCV-infected patients with fibrosis stage (F1 & F2). Participants were randomly assigned to two groups: Group 1 (Control group, n = 25) received standard direct-acting antiviral therapy for 3 months, while Group 2 (Zinc group, n = 25) received 50 mg/day of zinc sulfate in addition to the standard direct-acting antiviral therapy for the same duration.
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