Efficacy of Shear-Wave Elastography for Detecting Postoperative Cervical Lymph Node Metastasis in Papillary Thyroid Carcinoma.

Int J Endocrinol

Division of Endocrinology and Metabolism, Department of Internal Medicine, Soonchunhyang University Hospital, Soonchunhyang University College of Medicine, Seoul, Republic of Korea.

Published: September 2018

Aims: To evaluate shear-wave elastography (SWE) as a tool to detect postoperative cervical lymph node (LN) metastasis in patients with papillary thyroid carcinoma (PTC).

Methods: Forty-three LNs of 43 patients with PTC undergoing ultrasound (US) and SWE before ultrasound-guided fine-needle aspiration (FNA) for the evaluation of postoperative cervical LN recurrences were analyzed. The mean (), minimum (), maximum (), and standard deviation () of SWE elasticity indices were measured.

Results: Among 43 indeterminate or suspicious LNs, 12 were malignant and 31 were benign. The , , , and values were significantly higher in malignant LNs than in benign LNs (: 37.1 kPa in malignant versus 11.8 kPa in benign LNs, < 0.001; : 11.3 kPa versus 5.1 kPa, = 0.046; : 50.5 kPa versus 23.7 kPa, < 0.001; and : 7.8 kPa versus 4.1 kPa, = 0.006). had the highest accuracy (93.0%) when applied with a cut-off value of 37.5 kPa. It had a positive likelihood ratio of 25.83 and a diagnostic odds ratio of 150.0.

Conclusions: The shear elasticity index of , with higher likelihood ratios for malignant LNs, may help identify postoperative cervical LN metastasis in PTC patients with indeterminate or suspicious LNs.

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Source
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6142733PMC
http://dx.doi.org/10.1155/2018/9382649DOI Listing

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