The extracellular matrix plays both positive and negative roles in growth factor diffusion, a process critical for organ formation. In this issue of Developmental Cell, Wang et al. (2018) identify the extracellular matrix protein Anosmin1 as a key regulator of Fgf diffusion during sensory organ formation in zebrafish.
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http://dx.doi.org/10.1016/j.devcel.2018.09.004 | DOI Listing |
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