Neisseria cinerea is a commensal which usually resides in the human respiratory tract. Very rarely, the organism finds its way into the bloodstream causing severe bacteremia. So far, very few cases of Neisseria bacteremia have been reported. We report a case of a 78-year-old male, post-splenectomy, who presented with high fever, cough and shortness of breath. The patient was initially managed for septic shock with fluid resuscitations, vasopressors and broad-spectrum antibiotics. Later, the blood cultures grew gram-negative coccobacilli, Neisseria cinerea. The patient was successfully treated with intravenous ceftriaxone. This is the first case ever of Neisseria cinerea bacteremia in a post-splenectomy patient and ninth case overall. This case illustrates that the physicians should maintain heightened awareness for Neisseria cinerea bacteremia in post-splenectomy patients.
Download full-text PDF |
Source |
---|---|
http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6145752 | PMC |
http://dx.doi.org/10.7759/cureus.3007 | DOI Listing |
Folia Microbiol (Praha)
October 2024
Department of Natural and Life Sciences, Faculty of Sciences and Technology, University of Amine Elokkal El Hadj Moussa Eg Akhamoukh, 11039, Sersouf, Tamanrasset, Algeria.
Bacillus is well known for producing a wide range of compounds that inhibit microbial phytopathogens. From this perspective, we were interested in evaluating the biocontrol potential of 5 plant growth-promoting rhizobacteria Bacillus species (PGPR-Bacillus) on 21 microbial pectinolytic plant pathogens isolated from previous studies. Phytopathogenicity and in vivo biocontrol potential of PGPR curative and preventive treatments were investigated from this angle.
View Article and Find Full Text PDFFront Immunol
October 2024
Department of Veterinary Medicine, University of Cambridge, Cambridge, United Kingdom.
J Med Microbiol
August 2024
Department of Clinical Sciences, Institute of Tropical Medicine, 2000 Antwerp, Belgium.
Microb Genom
February 2024
Department of Biology, University of Oxford, Oxford, OX1 3SY, UK.
Mosaic alleles formed through horizontal gene transfer (HGT) have been instrumental to the rising incidence of ceftriaxone-resistant gonococcal infections. Although interspecies HGT of regions of the gene between and commensal species has been described, knowledge concerning which species are the most common contributors to mosaic alleles is limited, with most studies examining only a small number of alleles. Here, we investigated the origins of recombinant alleles through analyses that incorporated 1700 alleles from 35 513 isolates, comprising 15 different species.
View Article and Find Full Text PDFVaccine
December 2023
Department of Veterinary Medicine, University of Cambridge, Cambridge CB3 0ES, UK.
An affordable, accessible, and broadly protective vaccine is required to tackle the re-occurring bacterial meningococcal epidemics in Sub-Saharan Africa as well as an effective control of multi-drug resistant strains of gonococcus. Outer membrane vesicles (OMVs) secreted from Gram-negative bacteria represent an attractive platform for antigen delivery to the immune system and therefore for development of multi-component vaccines. In this study, we describe the generation of modified OMVs (mOMVs) from commensal biosafety-level 1 (BSL-1) Neisseria cinerea ATCC® 14685, which is phylogenetically close to the pathogenic bacteria Neisseria meningitidis and Neisseria gonorrhoeae.
View Article and Find Full Text PDFEnter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!