AI Article Synopsis
- The study investigates how various clinical and imaging factors affect the prognosis of patients with isolated brainstem infarction (BSI).
- A cohort of 300 patients who suffered non-cardiogenic BSI within the last week was examined, focusing on their clinical traits and the characteristics of the infarction.
- Findings reveal that those with infarctions involving multiple perforating brainstem arteries and who weren't prescribed statins at discharge had poorer outcomes one year later, with nearly 30% experiencing disability.
Article Abstract
Objective: The prognosis of patients with isolated brainstem infarction (BSI) differs on an individual patient basis. This study was undertaken to analyze the influences of different imaging and clinical features with the prognosis of patients with BSI.
Methods: The study population was derived from a multicenter study of intracranial atherosclerosis in China. In the present study, 300 patients were selected who had experienced non-cardiogenic brain stem infarction within the prior 7 days. Evaluations included clinical characteristics, location and size of the brainstem infarction, and whether the infarction was located in multiple perforating branches of the brainstem. Poor prognosis was defined as the presence of disability within 1 year from the onset of disease.
Results: In total, 281 patients were followed up at 1 year post-infarction. Of these 281 patients, 84 (29.9%) exhibited disability at 1 year; these patients showed a median National Institutes of Health Stroke Scale score of 6 on admission. Multiple logistic regression analysis showed that patients with BSI located in the territory of multiple perforating arteries, who were discharged without administration of statins, showed a poor 1-year prognosis.
Conclusion: Isolated BSI involving multiple perforating arteries, without statin medication at discharge, indicated poor prognosis for patients with BSI.
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6300943 | PMC |
| http://dx.doi.org/10.1177/0300060518788253 | DOI Listing |
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