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A one-pot, acid-, base-, and metal-free, multicomponent strategy has been developed to synthesize spiro thiochromene-oxindole derivatives as potential anti-inflammatory agents. The synthesized compounds were screened for their anti-inflammatory activity by inhibiting heat-induced Bovine Serum Albumin (BSA) denaturation assay, revealing moderate to good efficacy. Compounds 4e, 4k, and 4h exhibited the highest activity, inhibiting BSA denaturation by 90.
View Article and Find Full Text PDFSustainable nanomaterials: the role of Cyrene in optimising carbon nanotubes dispersion and filtration efficiency.
Front Chem
December 2024
Circa Renewable Chemistry Institute, Department of Chemistry, University of York, York, United Kingdom.
This study focuses on the fabrication and characterisation of single-walled carbon nanotube (SWCNT) buckypapers and polyethersulfone (PES) flat-sheet membranes using Cyrene, aiming toevaluate its efficacy as a green solvent for these applications. Pristine SWCNTs were dispersed inCyrene without surfactants and compared to N-Methyl-2-pyrrolidone (NMP) dispersions. Buckypapers were fabricated from these dispersions and characterised using Scanning ElectronMicroscopy (SEM), Atomic Force Microscopy (AFM), and infrared spectroscopy.
View Article and Find Full Text PDFCitizen science in eDNA monitoring for mediterranean monk seal conservation.
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Department of Biomedical Sciences, University of Edinburgh, Edinburgh, UK.
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View Article and Find Full Text PDFSustainable leather alternatives: High-performance and dyeable bio-based materials from fungal chitin and tannic acid.
Carbohydr Polym
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College of Biomass Science and Engineering, Key Laboratory of Leather Chemistry and Engineering of Ministry of Education, Sichuan University, Chengdu 610065, China; National Engineering Laboratory for Clean Technology of Leather Manufacture, Sichuan University, Chengdu 610065, China. Electronic address:
Leather alternatives (LAs) offer a promising solution to address the environmental and ethical concerns associated with traditional leather production relying animal hides and chemical tanning agents. However, synthetic polymer-based LAs, such as polyurethane and polyvinyl chloride, have limited broader applications due to their complex manufacture process, high emission of volatile organic compounds, and poor biodegradability. Herein, we present the development of biomass-based LAs fabricated by combining two low-cost natural components - fungal chitin and plant polyphenols (i.
View Article and Find Full Text PDFAcute Kidney Injury in Deceased Organ Donors: Risk Factors And Impacts on Transplantation Outcomes.
Transplant Direct
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Department of Nephrology, Institute for Clinical and Experimental Medicine, Prague, Czech Republic.
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