Sarcopenia and muscle weakness are responsible for considerable health care expenditure but little is known about these costs in the UK. To address this, we estimated the excess economic burden for individuals with muscle weakness regarding the provision of health and social care among 442 men and women (aged 71-80 years) who participated in the Hertfordshire Cohort Study (UK). Muscle weakness, characterised by low grip strength, was defined according to the Foundation for the National Institutes of Health criteria (men < 26 kg, women < 16 kg). Costs associated with primary care consultations and visits, outpatient and inpatient secondary care, medications, and formal (paid) as well as informal care for each participant were calculated. Mean total costs per person and their corresponding components were compared between groups with and without muscle weakness. Prevalence of muscle weakness in the sample was 11%. Mean total annual costs for participants with muscle weakness were £4592 (CI £2962-£6221), with informal care, inpatient secondary care and primary care accounting for the majority of total costs (38%, 23% and 19%, respectively). For participants without muscle weakness, total annual costs were £1885 (CI £1542-£2228) and their three highest cost categories were informal care (26%), primary care (23%) and formal care (20%). Total excess costs associated with muscle weakness were £2707 per person per year, with informal care costs accounting for 46% of this difference. This results in an estimated annual excess cost in the UK of £2.5 billion.
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http://dx.doi.org/10.1007/s00223-018-0478-1 | DOI Listing |
J Clin Med
December 2024
Department of Rehabilitation Medicine, Kyorin University Faculty of Medicine, Mitaka, Tokyo 181-8611, Japan.
Pusher behavior after stroke is an important sequela that interferes with rehabilitation and independence in activities of daily living. As represented by visual or vestibular feedback, conventional methods require substantial assistance and time commitments, but have limited effectiveness. A recent case series suggests that prone posture may alleviate pusher behavior in patients with acute stroke.
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December 2024
Department of Histology and Embryology, Shandong Second Medical University, Weifang 261053, China.
Amyotrophic lateral sclerosis (ALS), commonly known as motor neuron disease, is a neurodegenerative disorder characterized by the progressive degeneration of both upper and lower motor neurons. This pathological process results in muscle weakness and can culminate in paralysis. To date, the precise etiology of ALS remains unclear.
View Article and Find Full Text PDFBioengineering (Basel)
December 2024
School of Biomedical Engineering, Capital Medical University, Beijing 100071, China.
Thigh muscles greatly influence knee joint loading, and abnormal loading significantly contributes to the progression of knee osteoarthritis (KOA). Muscle weakness in KOA patients is common, but the specific contribution of each thigh muscle to joint loading is unclear. The gait data from 10 severe female KOA patients and 10 controls were collected, and the maximum isometric forces of the biceps femoris long head (BFL), semitendinosus (ST), rectus femoris (RF), vastus lateralis (VL), and vastus medialis (VM) were calibrated via ultrasound.
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December 2024
Department of Neurosurgery, Carle Foundation Hospital, Urbana, IL 61801, USA.
Microcirculation is an essential system that regulates oxygen and nutrients to cells and tissues in response to various environmental stimuli and pathophysiological conditions. Diabetes mellitus can cause microvascular complications including nephropathy, neuropathy, and retinopathy. The pathogenesis of microvascular dysfunction in diabetes is associated with hyperglycemia and the result of an interplay of various factors.
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November 2024
Neurology Unit, Department of Translational Medicine, Maggiore Della Carità Hospital, University of Piemonte Orientale, 28100 Novara, Italy.
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