Recently, snake-like robots are proposed to assist experts during medical procedures on internal organs via natural orifices. Despite their well-spelt advantages, applications in radiosurgery is still hindered by absence of suitable designs required for spatial navigations within clustered and confined parts of human body, and inexistence of precise and fast inverse kinematics (IK) models. In this study, a deeply-learnt damped least squares method is proposed for solving IK of spatial snake-like robot. The robot's model consists of several modules, and each module has a pair of serial-links connected with orthogonal twists. For precise control of the robot's end-effector, damped least-squares approach is used to minimize error magnitude in a function modeled over analytical Jacobian of the robot. This is iteratively done until an apt joint vector needed to converge the robot to desired positions is obtained. For fast control and singularity avoidance, a deep network is built for prediction of unique damping factor required for each target point in the robot's workspace. The deep network consists of 11 x 15 array of neurons at the hidden layer, and deeply-learnt with a huge dataset of 877,500 data points generated from workspace of the snake robot. Implementation results for both simulated and actual prototype of an eight-link model of the robot show the effectiveness of the proposed IK method. With error tolerance of 0.01 mm, the proposed method has a very high reachability measure of 91.59% and faster mean execution time of 9.20 (±16.92) ms for convergence. In addition, the method requires an average of 33.02 (±39.60) iterations to solve the IK problem. Hence, approximately 3.6 iterations can be executed in 1 ms. Evaluation against popularly used IK methods shows that the proposed method has very good performance in terms of accuracy and speed, simultaneously.
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http://dx.doi.org/10.1016/j.neunet.2018.06.018 | DOI Listing |
JMIR Med Inform
January 2025
Medical Big Data Research Center, Chinese PLA General Hospital, Beijing, China.
Background: Machine learning models can reduce the burden on doctors by converting medical records into International Classification of Diseases (ICD) codes in real time, thereby enhancing the efficiency of diagnosis and treatment. However, it faces challenges such as small datasets, diverse writing styles, unstructured records, and the need for semimanual preprocessing. Existing approaches, such as naive Bayes, Word2Vec, and convolutional neural networks, have limitations in handling missing values and understanding the context of medical texts, leading to a high error rate.
View Article and Find Full Text PDFJ Med Internet Res
January 2025
Department of Biomedical Informatics, School of Medicine, Emory University, Atlanta, GA, United States.
Background: The increasing use of social media to share lived and living experiences of substance use presents a unique opportunity to obtain information on side effects, use patterns, and opinions on novel psychoactive substances. However, due to the large volume of data, obtaining useful insights through natural language processing technologies such as large language models is challenging.
Objective: This paper aims to develop a retrieval-augmented generation (RAG) architecture for medical question answering pertaining to clinicians' queries on emerging issues associated with health-related topics, using user-generated medical information on social media.
J Chem Inf Model
January 2025
College of Pharmaceutical Sciences, Zhejiang University, Hangzhou 310058, China.
Predicting protein-protein interactions (PPIs) is crucial for advancing drug discovery. Despite the proposal of numerous advanced computational methods, these approaches often suffer from poor usability for biologists and lack generalization. In this study, we designed a deep learning model based on a coattention mechanism that was capable of both PPI and site prediction and used this model as the foundation for PPI-CoAttNet, a user-friendly, multifunctional web server for PPI prediction.
View Article and Find Full Text PDFJ Comput Assist Tomogr
November 2024
From the Department of Diagnostic Imaging and Nuclear Medicine.
Objective: Radiographic findings to identify central venous catheter misplacement in the arteries, which can cause lethal complications, have not been fully evaluated, and its training is difficult because it is rare. The purpose of this study is to clarify radiographic findings for differentiating central venous and misplaced arterial lines using virtual chest radiographs and elucidate their usefulness in training radiologists.
Methods: This retrospective study included 150 patients (mean age, 67 [SD, ±12] years; 97 men) who underwent colon cancer surgery between January 2018 and December 2020.
J Comput Assist Tomogr
November 2024
From the Carl E. Ravin Advanced Imaging Labs, Center for Virtual Imaging Trials, Department of Radiology.
Objective: Patient characteristics, iodine injection, and scanning parameters can impact the quality and consistency of contrast enhancement of hepatic parenchyma in CT imaging. Improving the consistency and adequacy of contrast enhancement can enhance diagnostic accuracy and reduce clinical practice variability, with added positive implications for safety and cost-effectiveness in the use of contrast medium. We developed a clinical tool that uses patient attributes (height, weight, sex, age) to predict hepatic enhancement and suggest alternative injection/scanning parameters to optimize the procedure.
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