AI Article Synopsis
- The study compares early nasal intermittent positive pressure ventilation (nIPPV) and nasal continuous positive airway pressure (nCPAP) for treating respiratory distress syndrome (RDS) in preterm infants born between 24 and 32 weeks of gestation.
- A total of 84 infants were randomized into two groups, with 42 receiving nIPPV and 42 receiving nCPAP, showing similar birth weights and gestational ages.
- The results indicated that the nIPPV group had a significantly lower need for endotracheal intubation and invasive mechanical ventilation compared to the nCPAP group, leading to the conclusion that nIPPV is more effective in this context without increasing early morbidity rates.
Article Abstract
Aims: To compare the effect of early nasal intermittent positive pressure ventilation (nIPPV) and nasal continuous positive airway pressure (nCPAP) in terms of the need for endotracheal ventilation in the treatment of respiratory distress syndrome (RDS) in preterm infants born between 24 and 32 gestational weeks.
Methods: This is a randomized, controlled, prospective, single-centered study. Forty-two infants were randomized to nIPPV and 42 comparable infants to nCPAP (birth weight 1356 ± 295 and 1359 ± 246 g and gestational age 29.2 ± 1.7 and 29.4 ± 1.5 weeks, respectively).
Results: The need for endotracheal intubation and invasive mechanical ventilation was significantly lower in the nIPPV group than the nCPAP group (11.9% and 40.5%, respectively, p < 0.05). There were no differences in the duration of total nasal respiratory support, duration of invasive mechanical ventilation, bronchopulmonary dysplasia or other early morbidities.
Conclusion: nIPPV compared with nCPAP reduced the need for endotracheal intubation and invasive mechanical ventilation in premature infants with RDS.
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| http://dx.doi.org/10.1093/tropej/fmy058 | DOI Listing |
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