Rejection sensitivity is associated with social-emotional maladjustment in both childhood and adulthood. However, less is known about the etiology of rejection sensitivity. The present study tests an etiological model for rejection sensitivity using a high-risk sample ( N = 227) with prospective data from infancy (i.e., 12 months) to adolescence (i.e., eighth grade). Evidence for social learning and attachment theories was demonstrated. In particular, family and parenting factors, such as family conflict and maternal harshness, were predictive of rejection sensitivity in adolescence. Implications for intervention and prevention efforts are discussed.
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http://dx.doi.org/10.1177/0146167218795486 | DOI Listing |
Iran J Kidney Dis
December 2024
Department of Urology, Maoming People's Hospital, Maoming, China.
Introduction: Autophagy related genes (ARGs) may play important roles in various biological processes involving kidney transplantation (KT); however, their expression characteristics are rarely used to study the relationship between autophagy and prognosis in KT patients. This study aims to construct a new autophagy related gene feature based on high-throughput sequencing datasets.
Methods: Differentially expressed ARGs (DEARGs) were identified in KT patients based on the Gene Expression Omnibus (GEO) database.
J Vis Commun Med
December 2024
Moletest (Scotland) Ltd, Edinburgh, United Kingdom.
Four versions of the novel Moletest on-device signal-processing analysis software, delivered on a single-application iPadPro11, were evaluated in pigmented skin lesions of patients sent for biopsy comparing its results with the lesion histology. The primary objective was to demonstrate that the nomela test provided at least 95 ± 2% sensitivity for not-melanoma. Proprietary software recognised the lesion perimeter, rejecting images with uncertain border, and performed analysis using non-scalar metrics of the image within the perimeter.
View Article and Find Full Text PDFInt J Biol Macromol
December 2024
Department of Industrial Engineering, University of Salerno, via Giovanni Paolo II, 132, 84084 Fisciano, Italy.
This research is focused on the formulation and testing of green visual pH-sensitive indicators based on natural extracts from Curcuma Longa (CUR) and Lambrusco wine pomace (LAM), an Italian wine variety, incorporated into rice starch/pectin/alginate matrixes for non-destructively detecting shrimps freshness in real-time. The effect of the mixed indicators and their synergic combination on the properties and performances of indicators was investigated. Both the extract and their combination showed pronounced pH responsiveness.
View Article and Find Full Text PDFPhys Rev E
November 2024
Department of Fibre and Polymer Technology, KTH Royal Institute of Technology, SE10044 Stockholm, Sweden and Wallenberg Wood Science Center, KTH Royal Institute of Technology, SE10044 Stockholm, Sweden.
Motivated by the limitations of conventional coarse-grained molecular dynamics for simulation of large systems of nanoparticles and the challenges in efficiently representing general pair potentials for rigid bodies, we present a method for approximating general rigid body pair potentials based on a specialized type of deep neural network that maintains essential properties, such as conservation of energy and invariance to the chosen origins of the particles. The network uses a specialized geometric abstraction layer to convert the relative coordinates of the rigid bodies to input more suitable to a conventional artificial neural network, which is trained together with the specialized layer. This results in geometric representations of the particles optimized for the specific potential.
View Article and Find Full Text PDFMol Cancer Ther
December 2024
Department of Radiation Oncology, University of Michigan Rogel Cancer Center, Ann Arbor, Michigan.
PARP inhibitors sensitize pancreatic ductal adenocarcinoma (PDAC) to radiation by inducing DNA damage and replication stress. These mechanisms also have the potential to enhance radiation-induced type I interferon (T1IFN)-mediated antitumoral immune responses. We hypothesized that the PARP inhibitor olaparib would also potentiate radiation-induced T1IFN to promote antitumor immune responses and sensitization of otherwise resistant PDAC to immunotherapy.
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