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Cancer vaccines: an update on recent achievements and prospects for cancer therapy.
Clin Exp Med
December 2024
Department of Virology, National Institute of Public Health NIH-National Research Institute, Warsaw, Poland.
Decades of basic and translational research have led to a momentum shift in dissecting the relationship between immune cells and cancer. This culminated in the emergence of breakthrough immunotherapies that paved the way for oncologists to manage certain hard-to-treat cancers. The application of high-throughput techniques of genomics, transcriptomics, and proteomics was conclusive in making and expediting the manufacturing process of cancer vaccines.
View Article and Find Full Text PDFSmartphone pregnancy apps: systematic analysis of features, scientific guidance, commercialization, and user perception.
BMC Pregnancy Childbirth
November 2024
Department Artificial Intelligence in Biomedical Engineering, Machine Learning and Data Analytics Lab, Friedrich-Alexander-Universität Erlangen-Nürnberg (FAU), Erlangen, Germany.
Background: Over 50% of pregnant women use pregnancy applications (apps). Some app s lack credibility, information accuracy, and evidence-based clinical advice, containing potentially harmful functionality. Previous studies have only conducted a limited analysis of pregnancy app functionalities, expert involvement/evidence-based content, used commercialization techniques, and user perception.
View Article and Find Full Text PDFA giant planet transiting a 3-Myr protostar with a misaligned disk.
Nature
November 2024
Department of Physics and Kavli Institute for Astrophysics and Space Research, Massachusetts Institute of Technology, Cambridge, MA, USA.
Astronomers have found more than a dozen planets transiting stars that are 10-40 million years old, but younger transiting planets have remained elusive. The lack of such discoveries may be because planets have not fully formed at this age or because our view is blocked by the protoplanetary disk. However, we now know that many outer disks are warped or broken; provided the inner disk is depleted, transiting planets may thus be visible.
View Article and Find Full Text PDFCaptains vs. All-Stars: Who makes better leaders?
PLoS One
November 2024
Department of Economics, Durham University, Durham, Durham, United Kingdom.
This study explores the impact of formally assigned leaders (team captains) and informal leaders (all-stars) on their teammates' productivity in basketball. It uses in-game injuries as random shocks to examine how the unexpected absence of leaders affects team and individual performance. The research employs a staggered difference-in-differences estimation, to study peer effects in high-stakes team environments.
View Article and Find Full Text PDFHigh-temperature Tl decay clarifies Pb dating in early Solar System.
Nature
November 2024
GSI Helmholtzzentrum für Schwerionenforschung GmbH, Darmstadt, Germany.
Article Synopsis
- Radioactive nuclei that live for millions of years help us understand the Sun's formation and the nucleosynthesis happening when it was born, with lead (Pb) being a key example.
- Recent measurements of the weak decay of ionized thallium (Tl) provided a more accurate half-life, which was found to be 4.7 times longer than previously thought, thus reducing uncertainty in our calculations.
- Using these improved decay rates, researchers calculated lead yields in asymptotic giant branch (AGB) stars, confirmed isolation times for solar material, and validated the theory that the Sun formed in a long-lived molecular cloud.
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