Applying both occupational safety and ambidexterity theories, we investigate which situation in organizations leads to a lower number of work-related road accidents: a single-priority situation focused on road safety, or a dual-priority situation in which both road safety and customer service are priorities. Occupational safety theory puts forward an 'either-or' approach in which employee safety must be the first priority, above and beyond all others. In contrast, the ambidexterity theory's 'both-and' approach suggests a simultaneous coexistence of priorities. Results from forty-three units in three organizations that make intensive use of work-related driving and aim to deliver good customer service are described. The results suggest that when the level of customer service priority was low, an increase in the level of road safety priority significantly decreased the number of road accidents. However, when the level of customer service priority was high, an increase in the level of road safety priority was not associated with less road accidents. The results show that work-related road accidents would be lower in a safety-first, single-priority situation compared to a dual-priority situation encompassing both road safety and customer service. We discuss the theoretical and practical implications of these results.
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http://dx.doi.org/10.1016/j.aap.2018.08.020 | DOI Listing |
Indian J Orthop
February 2025
Department of Orthopaedics, All India Institute of Medical Sciences (AIIMS), Phulwari Sharif, Aurangabad Road, Patna, Bihar 801507 India.
Background: The implementation of the standard Ponseti technique (SPT) in management of idiopathic clubfoot can be challenging due to the need for frequent travelling and long duration to achieve correction. The one week accelerated Ponseti technique (OWAPT) reduces the duration of correction to seven days and has been reported to be effective and safe. However, children still need to travel for change of cast.
View Article and Find Full Text PDFRSC Adv
January 2025
Department of Chemistry, Center of Excellence for Innovation in Chemistry (PERCH-CIC), Faculty of Science, Mahidol University Rama VI Road Bangkok 10400 Thailand
Two series of indolo[1,2-]quinolines (IQs), comprising six 6-trifluoromethylthio indolo[1,2-]quinolines and nine 6-arenesulfonyl indolo[1,2-]quinolines, were screened for their inhibitory activity against EGFR tyrosine kinase (EGFR-TK) using the ADP-Glo™ kinase assay. Among the 15 IQs screened, four compounds exhibited cytotoxic activity against a lung cancer cell line (A549) that was as potent as the known drug afatinib with lower cytotoxicity in Vero cells. In addition, while they displayed cytotoxic activity against a head and neck squamous cell carcinoma cell line (SCC cells), they were inactive against a colorectal cancer cell line (LS174T cells).
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January 2025
Department of Health Education, Nanjing Municipal Center for Disease Control and Prevention, No.3, Zizhulin Road, Nanjing, Jiangsu Province, 210003, China.
Background: PARP inhibitors (PARPis) have shown promising effectiveness for ovarian cancer. This network meta-analysis (PROSPERO registration number CRD42024503390) comprehensively evaluated the effectiveness and safety of PARPis in platinum-sensitive recurrent ovarian cancer (PSROC).
Methods: Articles published before January 6, 2024 were obtained from electronic databases.
J Gen Intern Med
January 2025
Department of Medicine, University of Toronto, Ontario, Canada.
Dig Dis Sci
January 2025
Infectious Diseases Department, Suining Central Hospital, Suining, Sichuan, China.
Background: The diagnosis and treatment of chronic abdominal pain related to the appendix have always been challenging. In the past, an appendectomy was the main approach for suspected chronic abdominal pain related to the appendix, but there was an associated risk of negative appendectomy. In recent years, cholangioscope-assisted endoscopic retrograde appendicitis therapy (ERAT) has been used to view the appendiceal cavity directly for flushing, stone removal, biopsy, and other operations, thereby achieving precise treatment.
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