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MiR-128-3p promotes hyperproliferation of keratinocytes and psoriasis-like inflammation by targeting SIRT1/HIF-1α.
Arch Dermatol Res
January 2025
Department of Dermatology, Zhejiang Provincial Hospital of Dermatology, Huzhou, 313200, China.
Psoriasis is a long-lasting inflammatory skin condition characterized by excessive keratinocyte growth. Recent studies have confirmed abnormal regulation of microRNAs (miRNAs/miRs) in individuals with psoriasis. This study aimed to investigate the function and specific mechanism of action of miR-128a-3p in interleukin-22 (IL-22)-stimulated HaCaT cells.
View Article and Find Full Text PDFNovel numerical and artificial neural computing with experimental validation towards unsteady micropolar nanofluid flow across a Riga plate.
Sci Rep
January 2025
Department of Mechanical Engineering, College of Engineering and Computer Sciences, Jazan University, P.O Box 45124, Jazan, Saudi Arabia.
Fluid flow across a Riga Plate is a specialized phenomenon studied in boundary layer flow and magnetohydrodynamic (MHD) applications. The Riga Plate is a magnetized surface used to manipulate boundary layer characteristics and control fluid flow properties. Understanding the behavior of fluid flow over a Riga Plate is critical in many applications, including aerodynamics, industrial, and heat transfer operations.
View Article and Find Full Text PDFIntroduction: Patients with end-stage renal disease usually undergo hemodialysis as a way of renal function replacement therapy which comes with a wide array of systemic and cutaneous complications. The aim of this study was to evaluate the most frequent dermatological manifestations including xerosis, pruritis and other nail, hair and oral conditions, as these are a very important aspect to be considered while managing the patients psychological and physical needs to improve their outcomes and quality of life.
Methods: This retrospective cross-sectional study was performed by selecting 77 patients on hemodialysis based on a certain criteria and data was then collected on a sheet using patients database on Hakeem National E-Health Program, in addition to information from interviews with patients during their hemodialysis sessions after taking an oral informed consent and insuring patients' privacy.
Orbital apex syndrome secondary to Sweet syndrome.
BMJ Case Rep
January 2025
Department of Ophthalmology, Rochdale Infirmary, Rochdale, UK.
Sweet syndrome (SS), or acute febrile neutrophilic dermatosis, is a dermatologic, auto-inflammatory disorder of unclear origin, often accompanied by systemic inflammation affecting various tissues, including the eyes. Common ocular manifestations include conjunctivitis but can extend to other ocular tissues. Orbital apex syndrome (OAS) involves damage to several cranial nerves transversing the orbital apex, leading to ophthalmoplegia and vision loss.
View Article and Find Full Text PDFApplications for Laser in Veterinary Dermatology.
Vet Clin North Am Small Anim Pract
January 2025
Auburn University, College of Veterinary Medicine, Department of Clinical Sciences, 1130 Wire Road, Auburn, AL 36849-5517, USA.
Laser usage in veterinary dermatology has increased in popularity over the last several decades. Carbon dioxide (CO) laser is the leading modality in surgical laser for veterinary dermatology because of its unmatched performance with soft tissue, particularly the skin. This laser cuts and coagulates tissue via the photothermal effect of laser energy when interacting with soft tissues with high water content, such as skin.
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