AI Article Synopsis
- Recent technological advances have significantly improved our understanding of the genetic factors and molecular traits of various brain tumors.
- These findings are leading to major changes in how these tumors are treated, potentially improving patient outcomes.
- The text reviews actionable mutations found in gliomas, meningiomas, and craniopharyngiomas, discussing their diagnostic and treatment implications, along with current research trials.
Article Abstract
In recent years, technologic advances have increased tremendously our understanding of the molecular characteristics and genetic drivers of a variety of brain tumors. These discoveries have led to paradigm shifts in the treatment of these tumor entities and may therefore have a considerable impact on the outcome of affected patients in the near future. Here, we provide a broad overview of recently discovered clinically actionable mutations that have been identified in three different primary brain tumors: gliomas, meningiomas, and craniopharyngiomas. We furthermore highlight the diagnostic and therapeutic implications of these findings and summarize recently published and ongoing trials.
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| http://dx.doi.org/10.1200/EDBK_199247 | DOI Listing |
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