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Negative symptoms in schizophrenia can be categorized in the symptom-dimensions of apathy (avolition, anhedonia and social withdrawal) and reduced expression (blunted affect and alogia). Based on the strong relevance for the quality of life and functional outcome during the course of an illness, a differentiated diagnostic and therapeutic approach is of high importance. Such a differentiation specifies primary negative symptoms (regarded as an integral part of schizophrenia) and secondary negative symptoms (regarded as a result of positive symptoms, comorbid depression, effects of antipsychotic medication, substance abuse or social deprivation). The following overview will summarize the various aspects of negative symptoms and discuss current diagnostic and therapeutic recommendations.
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