Giant cell tumor (GCT) of the bone is an aggressive lytic lesion, commonly treated with surgery. Denosumab is a relatively recently introduced osteoclast activation inhibitor used for neoadjuvant therapy of GCT. Here we report the case of a GCT of a rib undergoing extensive osteosclerosis on computed tomography imaging following treatment with denosumab.
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|---|---|
| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6137337 | PMC |
| http://dx.doi.org/10.1016/j.radcr.2018.04.005 | DOI Listing |
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