In this issue of , Fistonich et al. (https://doi.org/10.1084/jem.20180778) address how the bone marrow microenvironment supports diverse lineages through multiple developmental stages. Differential motility between pro- and preB cells results in differential IL-7 exposure, and, intriguingly, stromal cells respond to abnormal B cells by reducing .
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http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6170175 | PMC |
http://dx.doi.org/10.1084/jem.20181503 | DOI Listing |
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