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Mechanism exploration of intestinal mucus penetration of nano-se: Regulated by polysaccharides with different functional groups and molecular weights.
J Control Release
January 2025
State Key Laboratory of Food Science and Resources, China-Canada Joint Lab of Food Science and Technology (Nanchang), Key Laboratory of Bioactive Polysaccharides of Jiangxi Province, Nanchang University, Nanchang 330047, China.
Selenium deficiency associated with a high risk of many diseases remains a global challenge. Owing to the narrow margin between "nutrition-toxicity" doses of selenium, it is imperative to achieve accurate selenium supplement. Nano‑selenium (SeNPs) is a novel form of selenium supplement with low toxicity, but it could be trapped and removed by intestinal mucus, thus limiting its oral delivery.
View Article and Find Full Text PDFAdvances of Selenium in Poultry Nutrition and Health.
J Nutr
January 2025
Key Laboratory of Precision Nutrition and Food Quality, Department of Nutrition and Health, China Agricultural University, Beijing, China. Electronic address:
Selenium is widely acknowledged as an indispensable trace element for humans and various animals, including poultry. The addition of selenium in appropriate doses plays a crucial role in promoting poultry growth and reproduction. Conversely, both deficiency and excessive intake of selenium can pose significant threats to poultry health and production performance.
View Article and Find Full Text PDFAssessing the Nutrient Composition of a Carnivore Diet: A Case Study Model.
Nutrients
December 2024
Human Potential Centre, Faculty of Health and Environmental Sciences, Auckland University of Technology, Auckland 0632, New Zealand.
Background/objectives: The rise in chronic metabolic diseases has led to the exploration of alternative diets. The carnivore diet, consisting exclusively of animal products, has gained attention, anecdotally, for imparting benefit for inflammatory conditions beyond that possible by other restrictive dietary approaches. The aim was to assess the micronutrient adequacy of four versions of the carnivore diet against national nutrient reference values (NRVs).
View Article and Find Full Text PDFMicronutrient Deficiencies in Heart Failure and Relationship with Exocrine Pancreatic Insufficiency.
Nutrients
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Department of Cardiology, University Medical Centre Groningen, University of Groningen, 9713 GZ Groningen, The Netherlands.
Background: Micronutrient deficiencies are common and play a significant role in the prognosis of many chronic diseases, including heart failure (HF), but their prevalence in HF is not well known. As studies have traditionally focused on causes originating within the intestines, exocrine pancreatic insufficiency (EPI) has been overlooked as a potential contributor. The exocrine pancreas enables the absorption of various (fat-soluble) micronutrients and may be insufficient in HF.
View Article and Find Full Text PDFEffects and Impact of Selenium on Human Health, A Review.
Molecules
December 2024
School of Chemical Engineering, Guizhou Institute of Technology, Guiyang 550003, China.
Article Synopsis
- Selenium is an essential trace element that plays a vital role in human health through its incorporation in selenoproteins, which perform various biological functions, including antioxidant activity and immune system enhancement.
- More than 30 selenoproteins have been identified, with key examples like glutathione peroxidases (GPXs) and thioredoxin reductases (TrxRs) being studied for their health benefits.
- Due to the narrow margin between adequate and toxic doses of selenium, it's crucial to regulate intake levels to prevent deficiencies and toxicity, highlighting its importance in nutritional guidelines and public health.
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