Download full-text PDF |
Source |
|---|---|
| http://dx.doi.org/10.1038/s41588-018-0233-6 | DOI Listing |
Publication Analysis
Top Keywords
Similar Publications
Editorial: HBeAg-Positive Chronic Hepatitis B With Low HBsAg Levels-Exploring Clinical Significance of preS2 Deletion Mutations. Authors' Reply.
Aliment Pharmacol Ther
January 2025
Department of Laboratory Medicine, Nanjing Drum Tower Hospital, Affiliated Hospital of Medical School, Nanjing University, Nanjing, China.
Deep learning algorithm on H&E whole slide images to characterize alterations frequency and spatial distribution in breast cancer.
Comput Struct Biotechnol J
December 2024
Division of Pathology, European Institute of Oncology IRCCS, Milan, Italy.
The tumor suppressor is frequently mutated in hormone receptor-negative, HER2-positive breast cancer (BC), contributing to tumor aggressiveness. Traditional ancillary methods like immunohistochemistry (IHC) to assess functionality face pre- and post-analytical challenges. This proof-of-concept study employed a deep learning (DL) algorithm to predict mutational status from H&E-stained whole slide images (WSIs) of BC tissue.
View Article and Find Full Text PDFEvolutionary rescue effect can disappear under non-neutral mutations-a reply to Zhang et al. (2022).
Nat Commun
December 2024
MRC/CSO Social & Public Health Sciences Unit, University of Glasgow, Glasgow, G12 8QQ, UK.
Reply to: Evolutionary rescue effect can disappear under non-neutral mutations-a reply to Zhang et al. (2022).
Nat Commun
December 2024
Department of Mathematics, Bar-Ilan University, Ramat-Gan, Israel.
Investigating the influence of germline variants in chronic lymphocytic leukemia on cancer vulnerability.
Haematologica
November 2024
Department of Medical Oncology, Dana-Farber Cancer Institute, Boston, MA, USA; Department of Medicine, Harvard Medical School, Boston, MA.
Chronic lymphocytic leukemia (CLL) patients have an increased risk of secondary cancers, along with predisposition to CLL in their relatives. We have previously identified germline ATM variants as associated with CLL risk; here, we present their impact on predisposition to secondary neoplasms in CLL patients and their relatives. Patients enrolled in our tissue bank who had germline ATM status available were mailed a questionnaire between April 2022 and May 2023.
View Article and Find Full Text PDFWant AI Summaries of new PubMed Abstracts delivered to your In-box?
Enter search terms and have AI summaries delivered each week - change queries or unsubscribe any time!