AI Article Synopsis
- - The meta-analysis aimed to evaluate cognitive performance in schizophrenia patients using Trail Making Tests (TMT) and how socio-demographic factors influence cognitive impairments.
- - The researchers analyzed 19 studies with 1,095 schizophrenia patients and 324 controls, finding significant cognitive deficits (p<0.001) in patients compared to healthy controls on both TMT-A and B tests.
- - The study concluded that while schizophrenia patients showed impaired cognitive processing speed and flexibility, factors like substance abuse, education length, and illness duration did not significantly contribute to these cognitive impairments.
Article Abstract
Objective: The present meta-analysis aimed to analyze the cognitive performance of schizophrenia patients measured by Trail Making Tests (TMT) and the contribution of socio-demographic factors to cognitive impairments.
Methods: PubMed and PsycARTICLES databases were searched for the studies published between January 1985 and November 2017. Data were drawn from 19 studies encompassing 1095 patients and 324 controls. The effect size and heterogeneity were assessed with Comprehensive Meta-Analysis version 2 using random-effect model.
Results: Overall, the results showed that the schizophrenia patients performed significantly (p<0.001) worse than healthy controls in both TMT-A and B. However, concurrent substance abuse, clinical status (inpatient or outpatient), duration of education and duration of illness were not associated with cognitive impairment among the schizophrenia patients.
Conclusion: The present meta-analysis confirmed the cognitive processing speed and flexibility of schizophrenia patients were impaired. However, their duration of education, duration of illness and clinical status (inpatient or outpatient) were not the risk factors.
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Source |
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| http://www.ncbi.nlm.nih.gov/pmc/articles/PMC6212701 | PMC |
| http://dx.doi.org/10.30773/pi.2018.07.22 | DOI Listing |
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