We describe the microbiological characterization and clinical presentation of two fungemia cases caused by fluconazole-resistant Candida auris in neonatal intensive care unit of a hospital in Beijing, China. We advocate for the need of guidelines or recommendations to improve identification, surveillance, and implementation of infection control measures in Chinese hospitals.
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http://dx.doi.org/10.1016/j.jinf.2018.09.002 | DOI Listing |
J Glob Infect Dis
August 2024
Department of Infection Prevention and Control, Tokyo Medical University Hospital, Shinjuku-ku, Tokyo, Japan.
Introduction: Catheter-related persistent infections (CRPCI) may develop after catheter-related bloodstream infections (CRBSI) due to colonization of the newly inserted catheter. However, the optimal timing for new catheter insertion remains controversial. The aim of this study was to determine the clinical features of CRBSI due to species and CRPCI.
View Article and Find Full Text PDFMed Mycol Case Rep
December 2024
Université Paris Cité, Faculté de Médecine, APHP, Hôpital Necker Enfants malades, Service de Maladies Infectieuses et Tropicales, 149 rue de Sèvres, 75015, Paris, France.
is a recently reported yeast causing rare cases of fungemia. This species presents high minimum inhibitory concentrations (MICs) to fluconazole and echinocandins. We report an atypical metacarpophalangeal osteo-articular infection in a patient with Chronic Granulomatous Disease.
View Article and Find Full Text PDFPan Afr Med J
November 2024
Laboratory of Parasitology-Mycology, Military Hospital of Tunis, Tunis, Tunisia.
Invasive fungal infections (IFI) are emerging opportunistic diseases that occur mainly in immunocompromised patients. Our study aimed to analyze the epidemiology of IFIs in patients with hematological malignancies, and the prognostic factors. Our retrospective study included patients hospitalized in the hematology department between January 1, 2010, and August 31, 2020, and in whom the diagnosis of IFI was made according to the EORTC criteria 2008.
View Article and Find Full Text PDFJ Mycol Med
December 2024
Division of Pediatric oncology, Tata Memorial Centre, Homi Bhabha National Institute, Mumbai, Maharashtra, India.
Background: Candida species are one of the leading causes of invasive fungal infections in pediatric patients with cancer, resulting in increased treatment related morbidity and mortality. There is limited data with respect to demography and outcomes of candidemia among children with cancer, especially from lower-middle income countries.
Methods: In this retrospective observational study conducted over a 4-year Period (January-2017 to December-2021), children less than 15 years with cancer, treated at a tertiary oncology centre in India and diagnosed with candidemia were included.
Key Clinical Message: Fungal endocarditis is a rare but potentially fatal infection with significant diagnostic and management challenges. Antifungal therapy and surgical debridement are the preferred treatments in these cases. Antimicrobial therapy with multiple antifungal agents may be required in high-risk patients presenting with prolonged fever suspected of having fungal endocarditis.
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