From Dental to Mental Institutions: Elmer McKesson's Secondary Saturation with Nitrous Oxide.

J Anesth Hist

Anesthesiology and Perioperative Medicine, Case Western Reserve University School of Medicine, 11100 Euclid Ave, Cleveland, OH 44106-6031, USA; Oral and Maxillofacial Surgery, Case Western Reserve University School of Dental Medicine, 2124 Cornell Rd, Cleveland, OH 44106-3804, USA; Honorary Curator and Laureate of the History of Anesthesia, Wood Library-Museum of Anesthesiology, American Society of Anesthesiologists, 1061 American Ln, Schaumburg, IL 60173-4973, USA. Electronic address:

Published: July 2018

As popularized by Elmer McKesson, MD, "secondary saturation" with nitrous oxide could expose patients to a second burst of 100% laughing gas to relax their muscles to assist surgeons. On rare occasions, this technique could provide a second opportunity for hypoxic brain damage and possible admission postoperatively to insane asylums.

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Source
http://dx.doi.org/10.1016/j.janh.2018.04.001DOI Listing

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