NLRP12: The Monarch of the Gut.

Cell Host Microbe

Department of Medicine, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA; Women's Guild Lung Institute, Cedars-Sinai Medical Center, Los Angeles, CA 90048, USA. Electronic address:

Published: September 2018

Innate pattern recognition receptors have been implicated in the obesity-associated imbalance of gut microbiota. In this issue of Cell Host & Microbe, Truax et al. (2018) report that NLRP12 prevents high-fat-diet-induced obesity by maintaining beneficial short-chain fatty acid-producing microbiota.

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Source
http://dx.doi.org/10.1016/j.chom.2018.08.010DOI Listing

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