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http://dx.doi.org/10.1371/journal.ppat.1007213 | DOI Listing |
Ann Clin Lab Sci
November 2024
Department of Pediatrics, Division of Infectious Diseases, State University of New York Health Sciences University, Brooklyn, NY, USA.
Objective: To present the case of a solid organ transplant recipient with Histoplasmosis in New York City.
Case Report: We present a 39-year-old female liver transplant recipient, who experienced a two-week history of progressive shortness of breath and dyspnea on exertion that interfered with all activities of daily living. Physical examination by the team revealed the patient had a WBC of 11.
Mycoses
January 2025
Laboratorio de Micología y Diagnóstico Molecular-Cátedra de Parasitología y Micología-Bioquímica, Universidad Nacional del Litoral, Santa Fe, Argentina.
Background: Access to fungal disease diagnosis is crucial for reducing mortality, yet it varies widely across Argentina, especially outside Buenos Aires. In regions like Santa Fe and Paraná, where most healthcare facilities are under 150 beds, maintaining specialised mycology labs is challenging.
Objectives: This work describes the establishment and first-year results of a centralised Fungal Disease Response Centre (FDRC) and referral network serving this region, covering approximately 1 million inhabitants.
Mycoses
January 2025
Clinical Medicine Department, Miguel Hernández University, Elche, Spain.
Background: Systemic endemic mycoses are systemic fungal infections typically found in tropical and subtropical regions. Their global incidence is rising, including in nonendemic countries, mainly due to migration and international travel. They are a major cause of morbidity and mortality worldwide, especially in immunocompromised patients.
View Article and Find Full Text PDFInfect Dis Clin North Am
December 2024
Department of Medicine, Division of Infectious Disease, Johns Hopkins University School of Medicine, Boston, MA, USA; Division of Infectious Diseases, Transplant and Oncology Infectious Diseases, The Johns Hopkins University School of Medicine, 725 North Wolfe Street, Baltimore, MD 21205, USA.
This review provides an update of histoplasmosis, covering the changing epidemiology, pathogenesis, disease manifestations, diagnostic strategies, and management considerations for immunocompetent and immunocompromised populations.
View Article and Find Full Text PDFTranspl Infect Dis
December 2024
Department of Medicine, Division of Infectious Diseases, Washington University School of Medicine, St. Louis, Missouri, USA.
Background: Histoplasmosis is an important infection among transplant recipients. Few studies have described its epidemiology and outcomes in the modern era.
Methods: We conducted a retrospective analysis using medical records from a single center in the United States.
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