Although fractures of the elbow are extremely common in pediatric patients, the T-type distal humerus fracture is rare and offers unique challenges. The mechanism of injury may be similar to the adult counterpart and is usually caused by a fall onto a flexed elbow or from a direct blow. Diagnosing these injuries may be difficult. They often resemble extension-type supracondylar fractures, yet the treatment algorithm is quite different. In younger patients, percutaneous pinning remains a viable option, but for older adolescents, open reduction and internal fixation provides stable fixation at the elbow and the most reliable restoration of the articular surface. Appropriate imaging, careful radiographic diagnosis, and choice of surgical technique are of paramount importance when treating young patients with this injury. Most pediatric and adolescent patients with T-type distal humerus fractures have results better than those of adults but often worse than other elbow fractures in this age group.
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http://dx.doi.org/10.5435/JAAOSGlobal-D-17-00040 | DOI Listing |
Adult zebrafish fins regenerate to their original size regardless of damage extent, providing a tractable model of organ size and scale control. Gain-of-function of voltage-gated K channels expressed in fibroblast-lineage blastema cells promotes excessive fin outgrowth, leading to a long-finned phenotype. Similarly, inhibition of the Ca -dependent phosphatase calcineurin during regeneration causes dramatic fin overgrowth.
View Article and Find Full Text PDFJBJS Case Connect
July 2024
Children's Hospital of Georgia, Augusta University Health, Augusta, Georgia.
Case: A 10-year-old, postmenarchal girl presented to the emergency department with a closed, displaced, intercondylar T-type distal humerus fracture. Open reduction and internal fixation was performed 3 days following initial presentation. The patient healed but experienced elbow stiffness in the 7 months following the procedure.
View Article and Find Full Text PDFVideoGIE
March 2024
Center for Advanced Endoscopy, Division of Gastroenterology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts.
Static magnetic stimulation (SMS) is a form of non-invasive brain stimulation that alters neural activity and induces neural plasticity that outlasts the period of stimulation. This can modify corticospinal excitability or motor behaviours, suggesting that SMS may alter the intrinsic excitability of neurons. In mammalian neurons, the axon initial segment (AIS) is the site of action potential initiation and undergoes structural plasticity (changes in length and position from the soma) as a homeostatic mechanism to counteract chronic changes in neuronal activity.
View Article and Find Full Text PDFEur J Radiol Open
June 2024
Diagnostic Radiology, Department of Neuroradiology and Odontology, Center for Medical Imaging and Physiology, Skåne University Hospital, Lund, Sweden.
Objective: To systematically evaluate the ability of the CINA® LVO software to detect large vessel occlusions eligible for mechanical thrombectomy on CTA using conventional neuroradiological assessment as gold standard.
Methods: Retrospectively, two hundred consecutive patients referred for a brain CTA and two hundred patients that had been subject for endovascular thrombectomy, with an accessible preceding CTA, were assessed for large vessel occlusions (LVO) using the CINA® LVO software. The patients were sub-grouped by occlusion site.
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