Objective: To investigate the chemical constituents from the roots of Macleaya cordata.
Methods: The compounds were isolated and purified by silica gel,recrystallization and semi-preparative HPLC, their structures were eclucidated by physicochemistry properties, MS and NMR.
Results: Seven compounds were isolated and identified as 6-cyanodihydrochelerythrine (1),6-cyanodihydrochelilutine (2),dihydrochelirubine (3),6-methoxynorchelerythrine (4),dihydrosanguinarine (5),6-actonyldihydrosanguinarine (6) and stigmasterol (7).
Conclusion: Compounds 1,2 are new natural compounds and compound 4 is obtained from Macleaya cordata for the first time.
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